ArticleJournal of medical ethics2019
'Is it better not to know certain things?': views of women who have undergone non-invasive prenatal testing on its possible future applications.
Article in Journal of medical ethics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Decision-making for termination of pregnancy following non-invasive prenatal testing: a qualitative exploration of french, english and German healthcare professionals' perceptions and concerns.Reproductive health · 2025Article
- Blazing the Trail of Non-Invasive Prenatal Screening Expanded Use: Healthcare Providers' Perspectives.Prenatal diagnosis · 2025Article
- Indirect evidence of sex-selective abortion practices to the imbalanced sex ratio at birth in Australian migrant populations.PLOS global public health · 2025Article
- Patient interest in and clinician reservations on polygenic embryo screening: a qualitative study of stakeholder perspectives.Journal of assisted reproduction and genetics · 2024Article
- The risk of normative bias in reporting empirical research: lessons learned from prenatal screening studies about the prominence of acknowledged limitations.Theoretical medicine and bioethics · 2023Article
- Divergence Between Clinician and Patient Perspectives on Polygenic Embryo Screening: A Qualitative Study.medRxiv : the preprint server for health sciences · 2023Article
- Experiences of pregnant women with genome-wide non-invasive prenatal testing in a national screening program.European journal of human genetics : EJHG · 2023Article
- Non-Invasive Prenatal Testing for "Non-Medical" Traits: Ensuring Consistency in Ethical Decision-Making.The American journal of bioethics : AJOB · 2023Article
- Perceived Value of Prenatal Ultrasound Screening: A Survey of Pregnant Women.Maternal and child health journal · 2023Article
- Patient attitudes and preferences about expanded noninvasive prenatal testing.Frontiers in genetics · 2023Article
- Views of reproductive genetic carrier screening participants regarding screening for genes associated with non-syndromic hearing loss.Prenatal diagnosis · 2022Article
- Views of Canadian healthcare professionals on the future uses of non-invasive prenatal testing: a mixed method study.European journal of human genetics : EJHG · 2022Article
- Non-invasive prenatal testing (NIPT) and pregnant women's views on good motherhood: a qualitative study.European journal of human genetics : EJHG · 2022Article
- Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?The American journal of bioethics : AJOB · 2022Article
- Fetal information as shared information: using NIPT to test for adult-onset conditions.Monash bioethics review · 2021Article
- Access to Prenatal Testing and Ethically Informed Counselling in Germany, Poland and Russia.Journal of personalized medicine · 2021Article
- Collective Reflective Equilibrium in Practice (CREP) and controversial novel technologies.Bioethics · 2021Article
- A qualitative study of women and partners from Lebanon and Quebec regarding an expanded scope of noninvasive prenatal testing.BMC pregnancy and childbirth · 2021Article
- Birds of a Feather? Genetic Counseling, Genetic Testing, and Humanism.Cold Spring Harbor perspectives in medicine · 2020Review
- Sex selection and non-invasive prenatal testing: A review of current practices, evidence, and ethical issues.Prenatal diagnosis · 2020Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Non-invasive prenatal testing (NIPT) is at the forefront of prenatal screening. Current uses for NIPT include fetal sex determination and screening for chromosomal disorders such as trisomy 21 (Down syndrome). However, NIPT may be expanded to many different future applications. There are a potential host of ethical concerns around the expanding use of NIPT, as examined by the recent Nuffield Council report on the topic. It is important to examine what NIPT might be used for before these possibilities become consumer reality. There is limited research exploring views of women on possible future uses of NIPT, particularly those of women who have undergone NIPT. In this study, we examined the views of women who undertook NIPT previously on the acceptability of and interest levels in using NIPT for a number of current and possible future applications. These included several medical conditions encompassing psychiatric, neurodevelopmental and adult-onset conditions as well as non-medical traits such as intelligence. One thousand women were invited to participate and 235 eligible surveys were received. Women generally reported an interest in using NIPT for medical conditions that severely impacted quality of life and with an onset earlier in life and stressed the importance of the accuracy of the test. Concerns were raised about the use of NIPT for non-medical traits. Respondents indicated that termination of pregnancy was not their only reason for testing, particularly in the case of sex. These results can further inform the ethical debate around the increasing integration of NIPT into healthcare systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.