Evidence map›Paper›PMID 30679049›Full record

ArticlePsychiatry research2019

Virtual reality assessment of functional capacity in people with Schizophrenia: Associations with reduced emotional experience and prediction of functional outcomes.

Philip D Harvey, Anzalee Khan, Alexandra Atkins, Richard Se Keefe

Abstract readEvaluation Study
In one paragraph

Article in Psychiatry research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Philip D HarveyDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL; Research Service, Miami VA Healthcare System, Miami, FL. Electronic address: philipdharvey1@cs.com.
Anzalee KhanNathan S. Klein Psychiatric Institute, Orangeburg, NY; Verasci, Inc, Durham, NC.
Alexandra AtkinsVerasci, Inc, Durham, NC.
Richard Se KeefeVerasci, Inc, Durham, NC; Duke University, Institute for Brain Sciences, Durham, NC.

Funding

The Virtual Reality Functional Capacity Assessment Tool (VRFCAT) Validation StudyR44MH084240 · NIMH · VERASCI, LLC · PI ATKINS, ALEXANDRA STRICKLAND · 2012 to 2018
$3.4M
Computerized Interactive Assessment of Functional Skills for Schizophrenia Drug TR43MH084240 · NIMH · VERASCI, LLC · PI HURLEY, KOLLEEN, KEEFE, RICHARD S · 2009 to 2009
$137k
NIMH NIH HHS R43 MH084240NIMH NIH HHS R44 MH084240
6 · The paper itself

Abstract

Virtual Reality (VR) approaches have had considerable success in measurement of functional capacity. However, it is not clear if factors other than cognitive impairment influence performance on VR measures. Many people with schizophrenia have significant negative symptoms and they could reduce engagement in assessment. 158 patients with schizophrenia performed the VRFCAT, were tested with the MCCB, were rated with the PANSS, and were rated on everyday functioning. Scores for reduced emotional experience and reduced expression were derived. Reduced emotional experience, but not reduced expression, was correlated with socially relevant VRFCAT subtasks and real-world social functioning. Performance on the socially relevant subtasks, but not the solitary subtasks, shared variance with work outcomes. MCCB performance was associated with both subdomains, but socially relevant subtasks shared more variance. Patients with higher reduced emotional experience validly engaged in socially relevant VR simulations, as indexed by correlations with outcome measures. These patients had poorer performance on socially relevant tasks than on solitary tasks. The differential validity of solitary vs. socially relevant simulations was supported by differences in correlates, suggesting that assessments with a focus on performance of simulated socially relevant tasks could be developed.

Indexed as

Disability EvaluationNeuropsychological TestsSchizophrenic PsychologyVirtual RealityAdultEmotionsFemaleHumansMaleOutcome Assessment, Health CareSchizophreniaSocial Adjustment

Identifiers

PMID30679049
PMCPMC6592749

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.