Evidence map›Paper›PMID 30678515›Full record

ArticleThe Journal of international medical research2019

Short-term effect of intravitreal conbercept injection on major and macular branch retinal vein occlusion.

Yuan Tao, Chao Huang, Min Liu, Liyuan Sun, Linlin Li, Yuhua Wei, Xiaoting Yu, Hong Wang

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yuan Tao1 Department of Ophthalmology, Jinan Second People's Hospital, Jinan, Shandong, P.R. China.
Chao Huang2 Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Min Liu3 Department of Ophthalmology, Jinan Eighth People's Hospital, Jinan, Shandong, P.R. China.
Liyuan Sun2 Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Linlin Li4 Department of Ophthalmology, People's Hospital of Qihe County, Qihe, Shandong, P.R. China.
Yuhua Wei2 Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Xiaoting Yu2 Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.
Hong Wang2 Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan, Shandong, P.R. China.ORCID https://orcid.org/0000-0003-0433-7279
Qilu Hospital of Shandong University · CNQihe People's Hospital · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of intravitreal conbercept injection on major and macular branch retinal vein occlusion (BRVO).

methodsThis retrospective analysis involved 43 patients with BRVO (major BRVO n = 24; macular BRVO, n = 19) who were diagnosed by fluorescein fundus angiography (FFA) and injected with intravitreal conbercept. The following outcomes were measured at baseline and follow-up (1-6 months): best-corrected visual acuity (BCVA), central foveal thickness (CFT), total retinal volume in a 6-mm diameter section of the macula, choroidal thickness under the central fovea of the macula, relative area of retinal hemorrhage, complications, and times when repeated injection was performed.

resultsThere were significant differences between the two groups in terms of BCVA, CFT, and total retinal volume in a 6-mm diameter section of the macula at 6 months after treatment. Choroidal thickness under the central fovea of the macula and relative area of retinal hemorrhage showed no significant differences between the two groups at 6 months after treatment; however, they significantly differed from baseline measurements.

conclusionIn general, intravitreal injection of conbercept may have a better short-term effect in patients with macular BRVO than in patients with major BRVO.

Indexed as

AgedAged, 80 and overAngiogenesis InhibitorsFemaleFollow-Up StudiesHumansIntravitreal InjectionsMacular EdemaMaleMiddle AgedPrognosisRecombinant Fusion ProteinsRetinal Vein OcclusionRetrospective StudiesAngiogenesis InhibitorsKH902 fusion proteinRecombinant Fusion ProteinsBRVOcentral foveal thicknesschoroidal thicknessConberceptmacular BRVOretinal hemorrhageVEGFvisual acuity

Identifiers

PMID30678515
PMCPMC6421366
OpenAlexW2912576829

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.