Evidence map›Paper›PMID 30678234›Full record

ArticleCells2019

Manganese Suppresses the Haploinsufficiency of Heterozygous

Lavinia L Ruta, Ioana Nicolau, Claudia V Popa, Ileana C Farcasanu

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Evolutionary Aspects of TRPMLs and TPCs.International journal of molecular sciences · 2020
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lavinia L RutaDepartment of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, Sos. Panduri 90-92, 050663 Bucharest, Romania. lavinia.ruta@chimie.unibuc.ro.ORCID 0000-0001-9287-5485
Ioana NicolauDepartment of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, Sos. Panduri 90-92, 050663 Bucharest, Romania. ioana.nicolau@chimie.unibuc.ro.
Claudia V PopaDepartment of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, Sos. Panduri 90-92, 050663 Bucharest, Romania. valentina.popa@chimie.unibuc.ro.
Ileana C FarcasanuDepartment of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, Sos. Panduri 90-92, 050663 Bucharest, Romania. ileana.farcasanu@chimie.unibuc.ro.ORCID 0000-0002-4901-7896
University of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient potential receptor (TRP) channels are conserved cation channels found in most eukaryotes, known to sense a variety of chemical, thermal or mechanical stimuli. The

Indexed as

HaploinsufficiencyCalciumCytosolDiploidyHeterozygoteHydrogen PeroxideManganeseMutationOxidative StressSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTRPC Cation ChannelsVacuolesCalciumHydrogen PeroxideManganeseSaccharomyces cerevisiae ProteinsTRPC Cation ChannelsYvc1 protein, S cerevisiaecalciummanganeseoxidative stressSaccharomyces cerevisiaeTRP channelTRPY1

Identifiers

PMID30678234
PMCPMC6406398
OpenAlexW2911594115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.