Evidence map›Paper›PMID 30678193›Full record

Trial reportNutrients2019

Effects of Tart Cherry Juice on Biomarkers of Inflammation and Oxidative Stress in Older Adults.

Sheau C Chai, Kristina Davis, Zugui Zhang, Longying Zha, Kenneth F Kirschner

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Dark Sweet Cherry (Nutrients · 2023
    Trial
  7. Trial
  8. Trial
  9. Review
  10. Review
  11. Article
  12. Article
  13. Tart cherries (Frontiers in nutrition · 2026
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sheau C ChaiDepartment of Behavioral Health and Nutrition, College of Health Sciences, University of Delaware, Newark, DE 19716, USA. scchai@udel.edu.ORCID 0000-0003-3969-8912
Kristina DavisDepartment of Behavioral Health and Nutrition, College of Health Sciences, University of Delaware, Newark, DE 19716, USA. kristinacdavis1@gmail.com.
Zugui ZhangValue Institute, Christiana Care Health System, Newark, DE 19718, USA. zzhang@christianacare.org.
Longying ZhaDepartment of Nutrition and Food Hygiene, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China. lyzha@smu.edu.cn.
Kenneth F KirschnerCollege of Health Sciences, University of Delaware, Newark, DE 19716, USA. kirschne@udel.edu.

Funding

Cherry Research Committee of the Cherry Marketing Institute 15A00149
6 · The paper itself

Abstract

Inflammation and oxidative stress are important factors in the development of cardiovascular disease and atherosclerosis. The findings of our previous study suggest that 12 weeks consumption of tart cherry juice lowers the levels of systolic blood pressure (BP) and low-density lipoprotein (LDL) cholesterol in older adults. The present study investigated the effects of tart cherry juice on blood biomarkers of inflammation and oxidative stress. In this randomized-controlled clinical trial, a total of 37 men and women between the ages of 65⁻80 were randomly assigned to consume 480 mL of tart cherry juice or control drink daily for 12 weeks. Several blood biomarkers of inflammation and oxidative stress were assessed at baseline and after 12 weeks intervention. After the 12 weeks intervention, tart cherry juice significantly increased the plasma levels of DNA repair activity of 8-oxoguanine glycosylase (

Indexed as

Fruit and Vegetable JuicesPrunus aviumAgedAged, 80 and overBiomarkersFemaleGene Expression RegulationHumansInflammationMaleOxidative StressRandom AllocationBiomarkerscardiovascular risk factorsdietary interventioninflammationoxidative stresspolyphenolstart cherry

Identifiers

PMID30678193
PMCPMC6413159

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.