Evidence map›Paper›PMID 30678180›Full record

ArticleNutrients2019

Impact of Malnutrition on Long-Term Mortality in Elderly Patients with Acute Myocardial Infarction.

Klara Komici, Dino Franco Vitale, Angela Mancini, Leonardo Bencivenga, Maddalena Conte, Sandra Provenzano, Fabrizio Vincenzo Grieco, Lucia Visaggi, Ilaria Ronga, Antonio Cittadini and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Klara KomiciDepartment of Medicine and Health Sciences, University of Molise, Campobasso, Via Francesco De Sanctis, 1, 86100 Campobasso, Italy. klara.komici@unimol.it.
Dino Franco VitaleClinica San Michele, Via Appia 187, 81024 Maddaloni (CE), Italy. dinofranco.vitale@fastwebnet.it.ORCID 0000-0003-2754-3438
Angela ManciniDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. angelamancini0387@libero.it.
Leonardo BencivengaDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. leonardobencivenga@gmail.com.ORCID 0000-0002-9575-8337
Maddalena ConteDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. maddalena-conte@libero.it.
Sandra ProvenzanoDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. provenzanosandra@gmail.com.
Fabrizio Vincenzo GriecoDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. fabrizio.g82@hotmail.it.
Lucia VisaggiDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. luciavisaggi@gmail.com.
Ilaria RongaDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. ilariaronga87@gmail.com.ORCID 0000-0003-4699-9633
Antonio CittadiniDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. antonio.cittadini@unina.it.
Graziamaria CorbiDepartment of Medicine and Health Sciences, University of Molise, Campobasso, Via Francesco De Sanctis, 1, 86100 Campobasso, Italy. graziamaria.corbi@unimol.it.ORCID 0000-0002-3441-889X
Bruno TrimarcoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy. bruno.trimarco@unina.it.
Carmine MoriscoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy. carmine.morisco@unina.it.
Dario LeoscoDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. dleosco@unina.it.
Nicola FerraraDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. nicola.ferrara@unina.it.ORCID 0000-0002-6582-9851
Giuseppe RengoDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy. giuseppe.rengo@unina.it.ORCID 0000-0002-9701-0437
University of Naples Federico II · ITIstituti Clinici Scientifici Maugeri · ITUniversity of Molise · ITCasa di Cura San Michele · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalnutrition is a frequent condition in the elderly, and is associated with prolonged hospitalization and increased mortality. However, the impacts of malnutrition among elderly patients with acute myocardial infarction have not been clarified yet. METHODS AND

resultsWe enrolled 174 patients aged 65 years and over, admitted with the diagnosis of acute myocardial infarction (AMI), who underwent evaluation of nutritional status by Mini Nutritional Assessment (MNA) and evaluation of mortality risk by GRACE Score 2.0. All-cause mortality was the outcome considered for this study. Over a mean follow-up of 24.5 ± 18.2 months, 43 deaths have been registered (24.3%). Non-survivors were more likely to be older, with worse glomerular filtration rate, lower systolic blood pressure, lower albumin and MNA score, higher prevalence of Killip classification III-IV grade, and higher Troponin I levels. Multivariate Cox proportional analysis revealed that GRACE Score and MNA showed a significant and independent impact on mortality, (HR = 1.76, 95%, CI = 1.34⁻2.32, and HR = 0.56, 95% CI = 0.42⁻0.73, respectively). Moreover, the clinical decision curve revealed a higher clinical net benefit when the MNA was included, compared to the partial models without MNA.

conclusionNutritional status is an independent predictor of long-term mortality among elderly patients with AMI. MNA score in elderly patients with AMI may help prognostic stratification and identification of patients with, or at risk of, malnutrition in order to apply interventions to improve nutritional status, and maybe survival in this population.

Indexed as

AgedAged, 80 and overFemaleGeriatric AssessmentHumansMaleMalnutritionMyocardial InfarctionNutritional StatusNutrition AssessmentRisk Factorsacute myocardial infarctionelderlymini nutritional assessmentmortality

Identifiers

PMID30678180
PMCPMC6412515
OpenAlexW2900533225

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.