Evidence map›Paper›PMID 30677250›Full record

Trial reportBirth defects research2019

Suicide risk in adolescents with fetal alcohol spectrum disorders.

Mary J O'Connor, Larissa C Portnoff, Michael Lebsack-Coleman, Katrina M Dipple

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Birth defects research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  8. Fetal alcohol spectrum disorders.Nature reviews. Disease primers · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Mary J O'ConnorDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California.ORCID 0000-0001-6862-6139
Larissa C PortnoffDepartment of Psychology, Teachers College, Columbia University, New York City, New York.
Michael Lebsack-ColemanDepartment of Applied Social Psychology, Claremont Graduate University, Claremont, California.
Katrina M DippleDepartment of Genetics, University of Washington, Seattle Children's Hospital, Seattle, Washington.
Claremont Graduate University · USColumbia University · USSeattle Children's Hospital · USUniversity of California, Los Angeles · US

Funding

Neurochemical Correlates of Brain Abnormalities in Prenatal Alcohol ExposureR01AA025066 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEVITT, JENNIFER G., O'CONNOR, MARY J. · 2016 to 2019
$2.2M
Intervention to Reduce Alcohol Consumption in Youth Exposed to Alcohol PrenatallyU84DD000504 · DD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI O'CONNOR, MARY J. · 2009 to 2011
$897k
NCBDD CDC HHS U84 DD000504NIAAA NIH HHS R01 AA025066
6 · The paper itself

Abstract

backgroundThe teratogenic effects of prenatal alcohol exposure (PAE) have been extensively documented over the course of 45 years of research and psychiatric problems are pervasive in this population. In adults with PAE, suicidal risk is high but less is known about the suicidal risk in adolescents with fetal alcohol spectrum disorders (FASD). This study describes the prevalence of suicidal ideation and serious suicide attempts in a sample of 54 adolescents between the ages of 13 and 18 years with FASD.

methodsAdolescents were diagnosed with FASD using the Updated Clinical Guidelines for Diagnosing Fetal Alcohol Spectrum Disorders. The Children's Interview for Psychiatric Syndromes was used to identify those adolescents who experienced suicidal ideation and/or who had made a serious suicide attempt in the last 12 months.

resultsThe prevalence of suicidal behaviors in this sample was high with 35.2% of teens reporting incidences of suicidal ideation and 13.0% reporting at least one serious suicide attempt in the past year. This finding is in contrast to the 17.2% and 2.4% for ideation and serious attempts, respectively, reported in the general U.S. adolescent population. Alarmingly, 29.2% of males with FASD reported a serious suicide attempt which was 19½ times higher than national norms for males. No females reported attempts. Number of home placements and the presence of a depressive disorder contributed to study outcomes.

conclusionsFindings demonstrate the significant risk for suicidality in this population, particularly adolescent males, and the need to assess and treat this life threatening behavior.

Indexed as

Adolescent BehaviorDepressive DisorderFetal Alcohol Spectrum DisordersPrenatal Exposure Delayed EffectsSuicidal IdeationAdolescentFemaleHumansMalePregnancyPrevalenceRisk FactorsSex FactorsSuicide, AttemptedFASDfetal alcohol Spectrum disordersPAEprenatal alcohol exposuresuicide risk

Identifiers

PMID30677250
PMCPMC6650307
OpenAlexW2911449831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.