Evidence map›Paper›PMID 30676337›Full record

Observational studyCritical care medicine2019

Readmission Diagnoses After Pediatric Severe Sepsis Hospitalization.

Erin F Carlton, Joseph G Kohne, Manu Shankar-Hari, Hallie C Prescott

Abstract readObservational Study
In one paragraph

Observational study in Critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Parental Mental Health Care After Their Child's Pediatric Intensive Care Hospitalization.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Erin F CarltonDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI.
Joseph G KohneDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI.
Manu Shankar-HariIntensive Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Hallie C PrescottDepartment of Medicine, University of Michigan Health System, Ann Arbor, MI.

Funding

General pathways and personalized risk of morbidity after sepsisK08GM115859 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PRESCOTT, HALLIE CHRISTINE · 2015 to 2018
$776k
Department of Health 16/33/01Department of Health CS-2016-16-011Department of Health EME/16/33/01NIGMS NIH HHS K08 GM115859
6 · The paper itself

Abstract

objectivesSevere sepsis is a significant cause of healthcare use and morbidity among pediatric patients, but little is known about readmission diagnoses. We sought to determine the most common readmission diagnoses after pediatric severe sepsis, the extent to which post-sepsis readmissions may be potentially preventable, and whether patterns of readmission diagnoses differ compared with readmissions after other common acute medical hospitalizations.

designObservational cohort study.

settingNational Readmission Database (2013-2014), including all-payer hospitalizations from 22 states. PATIENTS: Four-thousand five-hundred twenty-eight pediatric severe sepsis hospitalizations, matched by age, gender, comorbidities, and length of stay to 4,528 pediatric hospitalizations for other common acute medical conditions.

interventionsNone. MEASUREMENTS AND MAIN

resultsWe compared rates of 30-day all cause, diagnosis-specific, and potentially preventable hospital readmissions using McNemar's chi-square tests for paired data. Among 5,841 eligible pediatric severe sepsis hospitalizations with live discharge, 4,528 (77.5%) were matched 1:1 to 4,528 pediatric hospitalizations for other acute medical conditions. Of 4,528 matched sepsis hospitalizations, 851 (18.8% [95% CI, 16.0-18.2]) were rehospitalized within 30 days, compared with 775 (17.1% [95% CI, 17.1-20.0]) of matched hospitalizations for other causes (p = 0.02). The most common readmission diagnoses were chemotherapy, device complications, and sepsis, all of which were several-fold higher after sepsis versus after matched nonsepsis hospitalization. Only 11.5% of readmissions were for ambulatory care sensitive conditions compared with 23% of rehospitalizations after common acute medical conditions.

conclusionsMore than one in six children surviving severe sepsis were rehospitalized within 30 days, most commonly for maintenance chemotherapy, medical device complications, or recurrent sepsis. Only a small proportion of readmissions were for ambulatory care sensitive conditions.

Indexed as

Anti-Bacterial AgentsChildCohort StudiesCritical CareDatabases, FactualFemaleHospitals, PediatricHumansMalePatient DischargePatient ReadmissionRisk FactorsSepsisUnited StatesAnti-Bacterial Agents

Identifiers

PMID30676337
PMCPMC6535212

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.