Evidence map›Paper›PMID 30676236›Full record

ArticleHuman vaccines & immunotherapeutics2019

Disparities in uptake of 13-valent pneumococcal conjugate vaccine among older adults in the United States.

John M McLaughlin, David L Swerdlow, Farid Khan, Oliver Will, Aaron Curry, Vincenza Snow, Raul E Isturiz, Luis Jodar

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pneumococcal Vaccine for Adults Aged ≥19 Years: Recommendations of the Advisory Committee on Immunization Practices, United States, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023
    Guideline
  2. Pooled it
  3. Pooled it
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  12. Open forum infectious diseases · 2025
    Article
  13. Review
  14. Association Between Social Vulnerability and Streptococcus pneumoniae Antimicrobial Resistance in US Adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Disparities in vaccination rates in solid organ transplant patients.Transplant infectious disease : an official journal of the Transplantation Society · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

John M McLaughlina Pfizer Vaccines , Collegeville , PA , USA.
David L Swerdlowa Pfizer Vaccines , Collegeville , PA , USA.
Farid Khana Pfizer Vaccines , Collegeville , PA , USA.
Oliver Willb IQVIA , Plymouth Meeting , PA , USA.
Aaron Currya Pfizer Vaccines , Collegeville , PA , USA.
Vincenza Snowa Pfizer Vaccines , Collegeville , PA , USA.
Raul E Isturiza Pfizer Vaccines , Collegeville , PA , USA.
Luis Jodara Pfizer Vaccines , Collegeville , PA , USA.
Pfizer (United States) · USIQVIA (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn September 2014, 13-valent pneumococcal conjugate vaccine (PCV13) was universally recommended for all US adults aged ≥65 years. Adult PCV13 coverage, including whether disparities in uptake exist, however, is not well-described.

methodsWe used a monthly series of cross-sectional analyses of administrative medical and prescription claims data collected by IQVIA and linked to sociodemographic data collected by Experian to estimate overall and subpopulation-level uptake of PCV13 among US adults aged ≥65 years.

resultsAmong adults aged ≥65 years, 43.3% received PCV13 by the end of November 2017. Race/ethnicity, annual household income, education status, and neighborhood urbanicity were strongly related to PCV13 uptake among adults aged ≥65 years. Lower uptake of PCV13 was observed for non-Hispanic black (36.3%) and Hispanic (30.0%) adults (vs 45.6% for non-Hispanic whites, P < .01), the poor (30.7% vs 54.2% among lowest vs highest income deciles, P < .01), adults with low educational status (33.0% vs 49.0% among those without high school education vs college educated, P < .01), and those living in rural communities (22.9%) or urban/inner-city (33.8%) areas (vs 45.8% in suburban areas, P < .01).

conclusionsPCV13 uptake among adults aged ≥65 occurred rapidly in the three years after universal recommendation in September 2014. Yet, poor and minority communities, rural and urban/inner-city areas, and communities with low educational attainment had substantially lower PCV13 coverage. These same populations are at increased risk of pneumococcal disease. In order to maximize the benefits of pneumococcal vaccination, further targeted and tailored interventions to increase PCV13 uptake in these underserved populations are still necessary.

Indexed as

AgedAged, 80 and overAge FactorsAntibodies, BacterialCross-Sectional StudiesEthnicityFemaleHealthcare DisparitiesHumansMalePneumococcal InfectionsPneumococcal VaccinesSocioeconomic FactorsStreptococcus pneumoniaeUnited StatesVaccination Coverage13-valent pneumococcal vaccineAntibodies, BacterialPneumococcal VaccinesVaccines, Conjugate13-valent pneumococcal conjugate vaccine (PCV13)Disparitiespneumococcal vaccinationrace/ethnicitysocioeconomic status (SES)

Identifiers

PMID30676236
PMCPMC6605819
OpenAlexW2913664322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.