ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019
Prevalence of oral side effects of chemotherapy and its relationship with periodontal risk: a cross sectional study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06465628 (Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients: a Randomized Controlled Trial
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of novel systemic cancer therapies on osseointegration and dental implant outcomes: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- The Role of Dental Oncology in Cancer Care: a Critical Component of Comprehensive Treatment, Education, and Interdisciplinary Collaboration- a Narrative Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Review
- Radiation-induced oral side effects in head and neck cancer: a scoping review and interdisciplinary recommendations.BMC oral health · 2026Article
- Sex difference in oral frailty Among older hospitalized cancer patients: a cross-sectional survey in taizhou, China.Frontiers in dental medicine · 2026Article
- ASSESSMENT OF ORO-DENTAL HEALTH PARAMETERS, FUNGAL INFECTION AND THE SEVERITY OF CHEMOTHERAPY INDUCED - ORAL MUCOSITIS: FINDINGS FROM A SOUTHWESTERN NIGERIAN TERTIARY CARE CENTRE.Annals of Ibadan postgraduate medicine · 2025Article
- Taste Dysfunction in Head and Neck Cancer: Pathophysiology and Clinical Management-A Comprehensive Review.Biomedicines · 2025Review
- Oral frailty and its influencing factors in patients with cancer undergoing chemotherapy: a cross-sectional study.BMC oral health · 2025Article
- Article
- Incidence of oral manifestations in hematological malignancy patients undergoing chemotherapy: prospective cohort study.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Prevalence and risk factors of chronic oral complications in head and neck cancer therapies: A retrospective study.Medicina oral, patologia oral y cirugia bucal · 2024Observational
- Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study.PloS one · 2023Observational
- Article
- Nutritional evaluation study based on NRS 2002, OPNI, and their combined use in patients with adverse drug reactions after chemotherapy: a cross-sectional study.Annals of translational medicine · 2022Article
- Xerostomia: an immunotherapy-related adverse effect in cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Application of Diffusion Kurtosis Imaging in Evaluating Acute Xerostomia in Nasopharyngeal Carcinoma Treated With Induction Chemotherapy Plus Concurrent Chemoradiotherapy.Frontiers in oncology · 2022Article
- Empowerment of Primary Healthcare Providers on the Prevention and Management of Dental or Oral Health Issues among Postchemotherapy Patients in Pandemic.Journal of healthcare engineering · 2022Article
- Chemotherapy-Induced Intestinal Microbiota Dysbiosis Impairs Mucosal Homeostasis by Modulating Toll-like Receptor Signaling Pathways.International journal of molecular sciences · 2021Review
- Experience of Parents with Children Undergoing Chemotherapy.SAGE open nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the prevalence of professionally reported oral side effects of chemotherapy and the self-reported oral side effects and whether both prevalences could be related to the periodontal risk of the patients.
methodsA cross-sectional study with patients undergoing chemotherapy treatment was carried out. Demographic, oral hygiene habits, and cancer-related data were collected while the patient was receiving the chemotherapy infusion. Patient's oral status, measured according to the oral-assessment guide for patients in hospital environments, patient-related outcomes (PROMs), measured by a visual analogue scale, and patient's periodontal risk were analyzed using validated questionnaires. Data was reported in means and standard deviations (SD) in quantitative variables and in counts, prevalence, and 95% confidence intervals (CI) in qualitative variables. ANOVA test and chi-squared tests were used to compare oral side effects among different periodontal risk groups.
resultsThree hundred sixty-nine patients were included in the study. The prevalence of professionally reported oral side effects was 86.99% (95% confidence interval CI 83.54%; 90.44%). The prevalence of self-reported oral side effects was 89.70% (95% CI 86.59; 92.82). The most common oral side effects were xerostomia (73.4%), dysgeusia (61.8%), and dry lips (54.2%). More oral alterations were found in patients with worse periodontal risk (p < 0.001).
conclusionsThe prevalence of oral side effects (professional or self-reported) is higher than 85% in patients undergoing chemotherapy. This prevalence increases as the risk of developing periodontal disease does.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.