ArticleNeuroradiology2019
Assessment of quantitative methods for enhancement measurement on vessel wall magnetic resonance imaging evaluation of intracranial atherosclerosis.
Article in Neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05907629 (Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Imaging endpoints of intracranial atherosclerosis using vessel wall MR imaging: a systematic review.Neuroradiology · 2021Pooled it
- Vessel Wall Magnetic Resonance Imaging Biomarkers of Symptomatic Intracranial Atherosclerosis: A Meta-Analysis.Stroke · 2021Pooled it
- Culprit intracranial plaque without substantial stenosis in acute ischemic stroke on vessel wall MRI: A systematic review.Atherosclerosis · 2019Pooled it
- Voxel-Wise Quantification and Multi-planar Visualization of Plaque Contrast Enhancement in Intracranial Vessel Wall MRI.medRxiv : the preprint server for health sciences · 2025Article
- Quantification of High-Resolution Contrast-Enhanced T1-Weighted Vessel Wall MRI for Predicting Disease Progression in Moyamoya Disease.Brain sciences · 2025Article
- Design of the "EAST" strategy in patients with symptomatic intracranial atherosclerotic stenosis.Frontiers in neurology · 2025Article
- Association of plaque characteristics with long-term stroke recurrence in patients with intracranial atherosclerotic disease: a 3D high-resolution MRI-based cohort study.European radiology · 2024Article
- Delayed Enhancement of Intracranial Atherosclerotic Plaque Can Better Differentiate Culprit Lesions: A Multiphase Contrast-Enhanced Vessel Wall MRI Study.AJNR. American journal of neuroradiology · 2024Article
- Quantitative analysis of unruptured intracranial aneurysm wall thickness and enhancement using 7T high resolution, black blood magnetic resonance imaging.Journal of neurointerventional surgery · 2022Article
- Association of Hypertension With Both Occurrence and Outcome of Symptomatic Patients With Mild Intracranial Atherosclerotic Stenosis: A Prospective Higher Resolution Magnetic Resonance Imaging Study.Journal of magnetic resonance imaging : JMRI · 2021Article
- Rabbit models of intracranial atherosclerotic disease for pathological validation of vessel wall MRI.The neuroradiology journal · 2021Article
- Utility of minimum intensity projection images based on three-dimensional CUBEThe British journal of radiology · 2021Article
- Article
- High-Resolution Vessel Wall Magnetic Resonance Imaging of the Middle Cerebral Artery: Comparison of 3D CUBE T1-Weighted Sequence with and without Fat Suppression.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- A pilot study using a machine-learning approach of morphological and hemodynamic parameters for predicting aneurysms enhancement.International journal of computer assisted radiology and surgery · 2020Article
- Effect of Time Elapsed since Gadolinium Administration on Atherosclerotic Plaque Enhancement in Clinical Vessel Wall MR Imaging Studies.AJNR. American journal of neuroradiology · 2019Article
- Clinical implications of vessel wall imaging-State-of-the-art review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceReview
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeQuantitative measures of vessel wall magnetic resonance imaging (vwMRI) for the evaluation of intracranial atherosclerotic disease (ICAD) offers standardization not available with previously used qualitative approaches that may be difficult to replicate.
methodsvwMRI studies performed to evaluate ICAD that had caused a stroke were analyzed. Two blinded reviewers qualitatively rated culprit lesions for the presence of enhancement on T1 delay alternating with nutation for tailored excitation (DANTE) SPACE images. At least 3 months later, quantitative analysis was performed of the same images, comparing lesion enhancement to reference structures. Cohen's kappa and intraclass correlation coefficients were calculated to assess agreement. Ratios of enhancement of lesions to references were compared to qualitative ratings.
resultsStudies from 54 patients met inclusion criteria. A mean of 49 (90.7%) lesions were qualitatively rated as enhancing, with good inter-rater agreement (κ = 0.783). Among reference structure candidates, low infundibulum demonstrated the highest inter-rater agreement on pre- and post-contrast imaging. The ratio of percentage increase in plaque signal following contrast to the same measure in low infundibulum demonstrated the highest agreement with qualitative assessment, with highest agreement seen with a ratio of 0.8 set as a threshold (κ = 0.675).
conclusionQuantitative metrics can yield objective data to better standardize techniques and acceptance of vwMRI evaluation of ICAD. The low infundibulum had the highest inter-rater agreement on both pre- and post-contrast images and is best suited as a normally enhancing reference structure. Such quantitative techniques should be implemented in future research of vwMRI for the evaluation of ICAD.
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