Evidence map›Paper›PMID 30675635›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2019

Consensus document for the diagnosis of peripheral bone infection in adults: a joint paper by the EANM, EBJIS, and ESR (with ESCMID endorsement).

Andor W J M Glaudemans, Paul C Jutte, Maria Adriana Cataldo, Victor Cassar-Pullicino, Olivier Gheysens, Olivier Borens, Andrej Trampuz, Klaus Wörtler, Nicola Petrosillo, Heinz Winkler and 2 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.

  1. EANM/SNMMI guideline/procedure standard for [European journal of nuclear medicine and molecular imaging · 2025
    Guideline
  2. Pooled it
  3. Pooled it
  4. Article
  5. Diagnostic accuracy of radiolabelled-WBC scintigraphy in patients with antibiotic therapy.European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Genomic and clinical characteristics ofMicrobiology spectrum · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Orthopedic infections associated with distinctFrontiers in cellular and infection microbiology · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 7 countries.

Andor W J M GlaudemansDepartment of Nuclear Medicine and Molecular Imaging, Medical Imaging Center, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands. a.w.j.m.glaudemans@umcg.nl.ORCID http://orcid.org/0000-0001-8081-0641
Paul C JutteDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Maria Adriana CataldoClinical and Research Department on of Infectious Diseases, "L. Spallanzani", IRCCS-Rome, Rome, Italy.
Victor Cassar-PullicinoDepartment of Diagnostic Imaging, Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Trust, Oswestry, Shropshire, UK.
Olivier GheysensDepartment of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Leuven, Belgium.
Olivier BorensDivision of Orthopaedic Surgery and Traumatology, Lausanne University Hospital, Lausanne, Switzerland.
Andrej TrampuzCenter for Muskuloskeletal Surgery, Charité - Universitätsmedicin Berlin, Berlin, Germany.
Klaus Wörtler69 Division Institut für Diagnostische und Interventionelle Radiologie, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Nicola PetrosilloClinical and Research Department on of Infectious Diseases, "L. Spallanzani", IRCCS-Rome, Rome, Italy.
Heinz WinklerOsteitis-Centre, Privatklinik Döbling, Vienna, Austria.
Alberto SignoreNuclear Medicine Unit, Faculty of Medicine and Psychology, Department of Medical-Surgical Sciences and Translational Medicine, "Sapienza" University, Rome, Italy.
Luca Maria SconfienzaUnit of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITUniversity Medical Center Groningen · NLCharité - Universitätsmedizin Berlin · DEKU Leuven · BERobert Jones and Agnes Hunt Orthopaedic Hospital · GBSapienza University of Rome · ITTUM Klinikum · DEUniversity of Lausanne · CHUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn adults with a suspicion of peripheral bone infection, evidence-based guidelines in choosing the most accurate diagnostic strategy are lacking. AIM AND

methodsTo provide an evidence-based, multidisciplinary consensus document on the diagnostic management of adult patients with PBIs, we performed a systematic review of relevant infectious, microbiological, orthopedic, radiological, and nuclear medicine literature. Delegates from four European societies (European Bone and Joint Infection Society, European Society of Microbiology and Infectious Diseases, European Society or Radiology, and European Association of Nuclear Medicine) defined clinical questions to be addressed, thoroughly reviewed the literature pertinent to each of the questions, and thereby evaluated the diagnostic accuracy of each diagnostic technique. Inclusion of the papers per statement was based on a PICO (Population/problem - Intervention/indicator - Comparator - Outcome) question following the strategy reported by the Oxford Centre for Evidence-based Medicine. For each statement, the level of evidence was graded according to the 2011 review of the Oxford Centre for Evidence-based Medicine. All approved statements were addressed taking into consideration the available diagnostic procedures, patient acceptance, tolerability, complications, and costs in Europe. Finally, a commonly agreed-upon diagnostic flowchart was developed.

Indexed as

DocumentationNuclear MedicineSocieties, ScientificAdultAnti-Bacterial AgentsEuropeEvidence-Based MedicineHumansOsteitisOsteomyelitisAnti-Bacterial AgentsDiagnosis of infectionGuidelineImagingOsteitisOsteomyelitisPeripheral bone infection

Identifiers

PMID30675635
PMCPMC6450853
OpenAlexW2912017198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.