ArticleJournal of the Endocrine Society2019
Predictive Accuracy of Surrogate Indices for Hepatic and Skeletal Muscle Insulin Sensitivity.
Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Empagliflozin improves insulin sensitivity in patients with recent acute coronary syndrome and newly detected dysglycaemia : Experiences from the randomized, controlled SOCOGAMI trial.Cardiovascular diabetology · 2023Trial
- Increased β-Cell Responsivity Independent of Insulin Sensitivity in Healthy African American Adults.The Journal of clinical endocrinology and metabolism · 2020Trial
- Insulin resistance in the 21st century: new takes on an old problem-2025 Diabetes, Diabetes Care, and Diabetologia Expert Forum.Diabetologia · 2026Review
- Impact of overweight and obesity on fasting insulin secretion in men and women without diabetes: effect sizes and mechanisms.Diabetologia · 2026Article
- Capturing metabolic syndrome: new thresholds for insulin resistance and novel body composition indices.International journal of obesity (2005) · 2026Article
- Postprandial Glycemia and Insulinemia Responses to a Standard and Modified Muffin in Healthy Adults and Adults with Type 2 Diabetes.Foods (Basel, Switzerland) · 2025Article
- Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes.Diabetes care · 2025Article
- Triglyceride and Glucose Index as an Optimal Predictor of Metabolic Syndrome in Lebanese Adults.Nutrients · 2024Article
- Determinants of hyperglucagonemia in pediatric non-alcoholic fatty liver disease.Frontiers in endocrinology · 2022Article
- Insulin sensitivity and pancreatic β-cell function in patients with primary aldosteronism.Endocrine · 2021Article
- Metabolic profiling of tissue-specific insulin resistance in human obesity: results from the Diogenes study and the Maastricht Study.International journal of obesity (2005) · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
contextSurrogate indices of muscle and hepatic insulin sensitivity derived from an oral glucose tolerance test (OGTT) are frequently used in clinical studies. However, the predictive accuracy of these indices has not been validated.
designIn this cross-sectional study, hyperinsulinemic-euglycemic glucose clamp with tritiated glucose infusion and a 75-g OGTT were performed in individuals (n = 659, aged 18 to 49 years, body mass index of 16 to 64 kg/m
resultsHIRI and MISI were correlated with their respective clamp-derived indices. HIRI was negatively related to Muscle-IS
conclusionOur findings indicate that the surrogate indices derived from an OGTT are accurate in predicting insulin sensitivity but are not tissue specific.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.