ReviewKidney international supplements2017
Complications of chronic kidney disease: current state, knowledge gaps, and strategy for action.
Review in Kidney international supplements, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 123 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Chinese Cohort Study of Chronic Kidney Disease Patients Followed on Smartphone Platform, a Multi-center Observational Study
Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis
Who cites it
123 citing papers in PubMed, 5 syntheses or guidelines pooled it, 249 citations in OpenAlex.
- Pooled it
- Effects of Exercise Training on Experimental Chronic Kidney Disease: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2026Pooled it
- Pooled it
- The effect of exercise training on quality of life in people with chronic kidney disease requiring dialysis. A systematic review with meta-analysis.Journal of nephrology · 2025Pooled it
- Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis.Frontiers in pharmacology · 2023Pooled it
- The effect of intradialytic resistance exercise on physical function and dialysis adequacy in patients on maintenance hemodialysis.PloS one · 2026Trial
- Effects of rhEPO-Fc on chronic renal anemia in Chinese patients undergoing maintenance hemodialysis: a multicenter, randomized, open-label, and phase 3 study.Renal failure · 2025Trial
- Review
- Treatment Patterns, Disease Management, and Quality of Life in Outpatients with CKD and Decreased eGFR: A Multicenter Prospective Observational Study in Greece.Journal of clinical medicine · 2026Article
- Alterations of Gene Expression and Signaling Pathway Activity in Venous Smooth Muscle Cells After Uremic Serum Exposure.International journal of molecular sciences · 2026Article
- Uremic Serum Alters Gene Expression Profiles and Signaling Pathway Activity in Porcine Arterial Smooth Muscle Cells.Biomolecules · 2026Article
- Genome-wide DNA methylation analysis revealed epigenetic mechanism underlying end-stage renal disease.Nature communications · 2026Article
- The interplay of GLP-1 receptor agonist use, chronic kidney disease and fracture risk in obese pAtients: a retrospective cohort study.British journal of clinical pharmacology · 2026Article
- The effect of dietary fiber based on fermentability and viscosity on the gut microbiome composition in chronic kidney disease: a systematic review of experimental and clinical trials.Research square · 2026Article
- Evaluation of medication regimen complexity and rehospitalization in older adults with chronic kidney disease: a retrospective cohort study.BMC geriatrics · 2026Article
- Morbidity and Mortality Rates in People with Diabetes Mellitus With an Active Charcot's Neuro-Osteoarthropathy: A 15-Year Single-Center Retrospective Analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Article
- Computational Frontiers in Arteriovenous Fistula Maturation: A Review of Fluid Dynamics and Machine Learning Models.Journal of the American Society of Nephrology : JASN · 2026Review
- Association between Alcohol Consumption and All-Cause Mortality in Patients Undergoing Hemodialysis: A Survival Analysis from the DIET-HD Cohort.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Pro-inflammatory cytokine IFN-γ protects against renal fibrosis by promoting E3 ubiquitin ligase Trim21-mediated Loxl2 degradation in tubular epithelial cells.Cell death & disease · 2026Article
- A Western Diet High in Phosphate Primes the Development of the CKD-Mineral Bone Disorder in an Alport Syndrome Model.Kidney360 · 2026Article
63 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 12 institutions in 11 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The International Society of Nephrology has adopted a proactive approach to defining the current state of kidney care and unmet needs through a multifaceted Closing the Gaps initiative. As part of this initiative, the International Society of Nephrology convened a meeting of experts to develop an approach to tackle acute kidney injury and chronic kidney disease (CKD). This manuscript expands on the recently published International Society of Nephrology CKD Roadmap and reports on the discussions of the working group assigned to the task of reviewing the global impact of complication of CKD. The working group defined the following goals: Goal 1: Optimize the management of anemia and endocrine and metabolic abnormalities associated with CKD. The impact of these conditions at a global level is not well understood, particularly in regions where renal replacement therapy is not readily available. Some treatment regimens may be affordable in low- and middle-income countries and if implemented, could have an impact on the burden of suffering associated with CKD. Goal 2: Improve the prevention and management of cardiovascular complications linked to CKD. Most research on cardiovascular complications of CKD has focused on atherosclerotic diseases (myocardial infarction, ischemic stroke, and peripheral gangrene). There has been growing recognition that other forms of cardiovascular diseases, such as heart failure, valvular disease and arrhythmias, have a major impact on patient outcomes. Much less is known about the mechanisms and treatment of these non-atherosclerotic complications. Goal 3: Improve the diagnosis and management of symptoms associated with CKD. Symptom management is one of the greatest challenges in the management of CKD, with limited knowledge about the mechanisms associated with the development of these common problems and how best to characterize them into usable clinical phenotypes. Improved understanding of the complications of CKD may alleviate suffering and prolong life among millions of people worldwide both in developed countries and in regions where renal replacement therapy is not widely available.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.