Evidence map›Paper›PMID 30675425›Full record

ReviewKidney international supplements2017

Closing the gap between evidence and practice in chronic kidney disease.

Meg J Jardine, Bertram Kasiske, Dwomoa Adu, Mona Alrukhaimi, Gloria E Ashuntantang, Shakti Basnet, Worawon Chailimpamontree, Jonathan C Craig, Donal J O'Donoghue, Vlado Perkovic and 5 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Kidney international supplements, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 8 countries.

Meg J JardineRenal & Metabolic Division, The George Institute for Global Health, University of New South Wales Sydney, New South Wales, Australia.
Bertram KasiskeDepartment of Medicine, Hennepin County Medical Center, Minneapolis, Minnesota, USA.
Dwomoa AduDepartment of Medicine and Therapeutics, School of Medicine and Dentistry, University of Ghana, Accra, Ghana.
Mona AlrukhaimiDepartment of Medicine, Dubai Medical College, Dubai, United Arab Emirates.
Gloria E AshuntantangFaculty of Medicine and Biomedical Sciences, Yaounde General Hospital, University of Yaounde I, Yaounde, Cameroon.
Shakti BasnetDepartment of Nephrology, Gautam Buddha Community Kidney Center, Butwal, Nepal.
Worawon ChailimpamontreeNephrology Division, Department of Medicine, Bhumibol Adulyadej Hospital, Bangkok, Thailand.
Jonathan C CraigDepartment of Nephrology, School of Public Health, University of Sydney, Sydney, New South Wales, Australia.
Donal J O'DonoghueDepartment of Renal Medicine, Salford Royal National Health Service (NHS) Foundation Trust, Salford, UK.
Vlado PerkovicThe George Institute for Global Health, University of New South Wales Sydney, New South Wales, Australia.
Neil R PoweDepartment of Medicine, University of California San Francisco School of Medicine, San Francisco, California, USA.
Charlotte J RobertsStandardisation, International Consortium for Health Outcomes Measurement, London, UK.
Yusuke SuzukiDepartment of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Tetsuhiro TanakaDivision of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan.
Katrin UhligClinical Development, Keryx Biopharmaceuticals, Boston, Massachusetts, USA.
Bhumibol Adulyadej Hospital · THConcord Repatriation General Hospital · AUDubai Medical College · AEJuntendo University · JPNational Health Service · GBSan Francisco General Hospital · USThe University of Sydney · AUThe University of Tokyo · JPTufts University · USUniversité de Yaoundé I · CMUniversity of Ghana · GHUniversity of Minnesota · USUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are major gaps between our growing knowledge of effective treatments for chronic kidney disease (CKD), and the delivery of evidence-based therapies to populations around the world. Although there remains a need for new, effective therapies, current evidence suggests that many patients with CKD are yet to fully realize the benefits of blood pressure-lowering drugs (with and without reducing proteinuria with renin-angiotensin system blockade), wider use of statins to reduce atherosclerotic cardiovascular disease events, and better glycemic control in both type 1 and type 2 diabetes. There are many barriers to optimizing evidence-based nephrology care around the world, including access to health care, affordability of treatments, consumer attitudes and circumstances, the dissemination of appropriate knowledge, the availability of expertise and structural impediments in the delivery of health care. Further investment in implementation science that addresses the major barriers to effective care in a cost-effective manner could yield both local and global benefits.

Indexed as

chronic kidney diseaseimplementationtreatment gap

Identifiers

PMID30675425
PMCPMC6341014
OpenAlexW2756405988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.