ReviewKidney international supplements2016
Electrophysiological and clinical consequences of hyperkalemia.
Review in Kidney international supplements, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Safety and efficacy of new potassium binders on hyperkalemia management in patients with heart failure: a systematic review and meta-analysis of randomized controlled trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Pooled it
- Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology.Journal of nephrology · 2019Guideline
- Population Pharmacodynamic Dose-Response Analysis of Serum Potassium Following Dosing with Sodium Zirconium Cyclosilicate.Clinical pharmacokinetics · 2024Trial
- Randomized Double-Blind Trial of WS016 in Chinese Patients With Hyperkalemia.Kidney international reports · 2026Article
- The Potential Impact of Serum Sodium and Potassium Levels on Sensorineural Hearing Loss and Tinnitus.Journal of clinical medicine · 2026Article
- Sinus arrest consequence of moderate hyperkalemia: a case report.Oxford medical case reports · 2025Article
- Monitoring serum potassium concentration in patients with severe hyperkalemia: the role of bloodless artificial intelligence-enabled electrocardiography.Clinical kidney journal · 2025Article
- EMCREG-International Multidisciplinary Consensus Panel on Management of Hyperkalemia in Chronic Kidney Disease and Heart Failure.Cardiorenal medicine · 2025Review
- Association of hyperkalaemia with electrocardiographic changes at a tertiary centre in South Africa.Journal of the colleges of medicine of South Africa · 2025Review
- Review
- Hyperkalemia During Prolonged Anesthesia in a Greyhound.Case reports in veterinary medicine · 2024Article
- Managing Hyperkalemia in the Modern Era: A Case-Based Approach.Kidney international reports · 2023Review
- First 24-Hour Potassium Concentration and Variability and Association with Mortality in Patients Requiring Continuous Renal Replacement Therapy in Intensive Care Units: A Hospital-Based Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- Management of hyperkalemia during treatment with mineralocorticoid receptor blockers: findings from esaxerenone.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Review
- Article
- Acute hyperkalemia in the emergency department: a summary from a Kidney Disease: Improving Global Outcomes conference.European journal of emergency medicine : official journal of the European Society for Emergency Medicine · 2020Review
- Severe Hyperkalemia, a Case Report.Journal of education & teaching in emergency medicine · 2020Article
- Renal Failure Patients in Disasters.Disaster medicine and public health preparedness · 2019Article
- Ranolazine Induced Bradycardia, Renal Failure, and Hyperkalemia: A BRASH Syndrome Variant.Case reports in medicine · 2019Article
- Hyperkalemia constitutes a constraint for implementing renin-angiotensin-aldosterone inhibition: the widening gap between mandated treatment guidelines and the real-world clinical arena.Kidney international supplements · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the potentially life-threatening consequences of hyperkalemia, symptoms are often absent or mild. However, when hyperkalemia has been recognized, evaluation of vital signs is essential for determining hemodynamic stability and identifying the presence of cardiac arrhythmias related to the hyperkalemia. Quite commonly, and depending on the severity and rapidity of onset, hyperkalemia may be associated with substantial electrocardiographic (EKG) changes that can lead to death if proper interventions are not instituted. Through its effects on the resting membrane potential and threshold potential of excitable cells, hyperkalemia is a potentially life-threatening disorder. Symptoms and physical examination findings are often absent. Once identified, the entire clinical picture must be taken into account, including an assessment of hemodynamic stability, the presence of other electrolyte abnormalities, and an EKG evaluation. While there is a typical progression of EKG findings based on hyperkalemia severity, EKG manifestations are myriad and their evolution may be unpredictable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.