Evidence map›Paper›PMID 30675142›Full record

ArticleJournal of geriatric cardiology : JGC2018

Applicability of the PRECISE-DAPT score in elderly patients with myocardial infarction.

Carme Guerrero, Albert Ariza-Solé, Francesc Formiga, Manuel Martínez-Sellés, María T Vidán, Jaime Aboal

Abstract read
In one paragraph

Article in Journal of geriatric cardiology : JGC, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Epidemiology, Pathophysiology, and Management of Coronary Artery Disease in the Elderly.The International journal of angiology : official publication of the International College of Angiology, Inc · 2022
    Article
  8. Cardiovascular prevention in elderly patients.Journal of geriatric cardiology : JGC · 2022
    Article
  9. Review
  10. Review
  11. Validation of the 4-Item PRECISE-DAPT Score: A SWEDEHEART Study.Journal of the American Heart Association · 2021
    Article
  12. Acute Coronary Syndrome in the Older Patient.Journal of clinical medicine · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Non-ST elevation acute coronary syndrome in the elderly.Journal of geriatric cardiology : JGC · 2020
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carme GuerreroDepartment of Cardiology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona.
Albert Ariza-SoléDepartment of Cardiology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona.
Francesc FormigaGeriatrics Medicine Unit, Internal Medicine Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona.
Manuel Martínez-SellésDepartment of Cardiology, Hospital General Universitario Gregorio Marañón, Madrid.
María T VidánGeriatrics Medicine Department, Hospital General Universitario Gregorio Marañón, Madrid.
Jaime AboalDepartment of Cardiology, Hospital Universitari Josep Trueta, Girona.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly patients with acute coronary syndromes (ACS) are at higher risk both for ischemic and bleeding complications. Current guidelines recommend the PRECISE-DAPT score for bleeding risk stratification in this setting, but no study assessed its applicability in elderly patients. This study aimed to assess the performance of the PRECISE-DAPT score in a series of non-selected elderly patients with ACS from routine clinical practice.

methodsThe IFFANIAM registry included prospectively patients aged ≥ 75 years with ST segment elevation myocardial infarction (STEMI). Main outcome measured was the incidence of relevant bleeding after discharge (bleeding leading to hospital readmission, need for transfusion, intervention, stop of antithrombotic drugs or death). Bleeding risk was classified: (A) according to PRECISE-DAPT values above or not the recommended cut-off point (≥ 25); and (B) according to the quartiles of PRECISE-DAPT values observed in the IFFANIAM series (Q1: < 30; Q2: 30-35; Q3: 36-44; Q4: ≥ 45).

resultsA total of 208 patients were included. Mean age was 81.9 ± 4.5 years. Most patients (92.6%) had a PRECISE-DAPT value > 25. A total of 25 patients (12.0%) had bleeding events and 49 patients (23.6%) died. No significant differences regarding the incidence of bleeding were observed according to the recommended cutt of point ≥ 25. However, a progressive increase in the incidence of bleeding was observed across PRECISE-DAPT quartiles observed in this series (

conclusionsThe vast majority of elderly patients have PRECISE-DAPT values above the recommended cut-off point for bleeding risk. Using different cut-off points could be a more rational approach for predicting bleeding risk in these complex patients.

Indexed as

Acute coronary syndromesBleedingPrognosisThe elderly

Identifiers

PMID30675142
PMCPMC6330266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.