Evidence map›Paper›PMID 30674958›Full record

ArticleScientific reports2019

Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice.

Ju Hwan Kim, Yang Hoon Huh, Jae-Hun Lee, Jae Yun Jung, Seung Cheol Ahn, Hak Rim Kim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ju Hwan KimDepartment of Pharmacology, College of Medicine, Dankook University, Cheonan-si, Chungnam, South Korea.
Yang Hoon HuhElectron Microscopy Research Center, Korea Basic Science Institute, Ochang, Chungbuk, South Korea.
Jae-Hun LeeDepartment of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University, Cheonan-si, Chungnam, South Korea.
Jae Yun JungDepartment of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University, Cheonan-si, Chungnam, South Korea.
Seung Cheol AhnDepartment of Physiology, College of Medicine, Dankook University, Cheonan-si, Chungnam, South Korea.
Hak Rim KimDepartment of Pharmacology, College of Medicine, Dankook University, Cheonan-si, Chungnam, South Korea. hrkim@dankook.ac.kr.
Dankook University · KRKorea Basic Science Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we measured the spontaneous post synaptic currents (sPSCs) at the post synaptic principle cells of the medial nucleus of the trapezoid body (MNTB) in early postnatal mice after exposure to 1850 MHz radiofrequency electromagnetic fields (RF-EMF). sPSC frequencies and amplitudes were significantly increased in the RF-EMF exposed group. Moreover, the number of synaptic vesicles in the calyx of Held was significantly increased in presynaptic nerve terminals. Following RF-EMF exposure, the number of docking synaptic vesicles in the active zone increased, thereby expanding the total length of the presynaptic active zone in the calyx of Held. These data suggest that the increased sPSCs are a result of greater synaptic vesicle release from presynaptic nerves. However, we found no morphological changes in the inner hair cell ribbon synapses. Further, there were no significant changes in the hearing threshold of the auditory brainstem response at postnatal day 15. Our results indicate that exposure to RF-EMF at an early postnatal stage might directly affect brainstem auditory circuits, but it does not seem to alter general sound perception.

Indexed as

Evoked Potentials, Auditory, Brain StemSynaptic TransmissionAcebutololAnimalsAnimals, NewbornMice, Inbred ICRRadio WavesSynaptic VesiclesTrapezoid BodyAcebutolol

Identifiers

PMID30674958
PMCPMC6344504
OpenAlexW2919552402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.