Evidence map›Paper›PMID 30674827›Full record

ReviewGels (Basel, Switzerland)2018

Application of Composite Hydrogels to Control Physical Properties in Tissue Engineering and Regenerative Medicine.

Cassidy Sheffield, Kaylee Meyers, Emil Johnson, Rupak M Rajachar

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Advanced Bio-Based Polymers for Astrocyte Cell Models.Materials (Basel, Switzerland) · 2021
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cassidy SheffieldDepartment of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA. cmhyde@mtu.edu.
Kaylee MeyersDepartment of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA. kmmeyers@mtu.edu.
Emil JohnsonDepartment of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA. emilj@mtu.edu.
Rupak M RajacharDepartment of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA. rupakr@mtu.edu.

Funding

Adhesive PEG-fibrinogen nitric oxide releasing hydrogels for use as a wound healiR15GM112082 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI RAJACHAR, RUPAK M · 2015 to 2015
$326k
NIGMS NIH HHS R15 GM112082NIH HHS R15GM112082
6 · The paper itself

Abstract

The development of biomaterials for the restoration of the normal tissue structure⁻function relationship in pathological conditions as well as acute and chronic injury is an area of intense investigation. More recently, the use of tailored or composite hydrogels for tissue engineering and regenerative medicine has sought to bridge the gap between natural tissues and applied biomaterials more clearly. By applying traditional concepts in engineering composites, these hydrogels represent hierarchical structured materials that translate more closely the key guiding principles required for improved recovery of tissue architecture and functional behavior, including physical, mass transport, and biological properties. For tissue-engineering scaffolds in general, and more specifically in composite hydrogel materials, each of these properties provide unique qualities that are essential for proper augmentation and repair following disease and injury. The broad focus of this review is on physical properties in particular, static and dynamic mechanical properties provided by composite hydrogel materials and their link to native tissue architecture and, ultimately, tissue-specific applications for composite hydrogels.

Indexed as

compositescontrolled physical propertieshydrogelstissue engineering

Identifiers

PMID30674827
PMCPMC6209271

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.