Evidence map›Paper›PMID 30674789›Full record

ReviewGels (Basel, Switzerland)2018

Stimuli-Responsive Cationic Hydrogels in Drug Delivery Applications.

G Roshan Deen, Xian Jun Loh

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Dendrimers-based Hydrogels and Nanogels for Drug Delivery.Current pharmaceutical biotechnology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Pharmaceutics · 2023
    Article
  9. Review
  10. Preliminary Investigation ofGels (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Synthesis of pH and Glucose Responsive Silk Fibroin Hydrogels.International journal of molecular sciences · 2021
    Article
  17. Article
  18. Review
  19. Annealing Supramolecular Gels by a Reaction Relay.Chemistry of materials : a publication of the American Chemical Society · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

G Roshan DeenSoft Materials Laboratory, Natural Sciences and Science Education AG, National Institute of Education, Nanyang Technological University, 1-Nanyang Walk, Singapore 637616, Singapore. roshan.gulam@nie.edu.sg.
Xian Jun LohInstitute of Materials Research and Engineering, 2-Fusionopolis Way, Singapore 138634, Singapore. lohxj@imre.a-star.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimuli-responsive, smart, intelligent, or environmentally sensitive polymers respond to changes in external stimuli such as pH, temperature, ionic strength, surfactants, pressure, light, biomolecules, and magnetic field. These materials are developed in various network architectures such as block copolymers, crosslinked hydrogels, nanogels, inter-penetrating networks, and dendrimers. Stimuli-responsive cationic polymers and hydrogels are an interesting class of "smart" materials that respond reversibly to changes in external pH. These materials have the ability to swell extensively in solutions of acidic pH and de-swell or shrink in solutions of alkaline pH. This reversible swelling-shrinking property brought about by changes in external pH conditions makes these materials useful in a wide range of applications such as drug delivery systems and chemical sensors. This article focuses mainly on the properties of these interesting materials and their applications in drug delivery systems.

Indexed as

cationic polymersdrug-delivery systemsheterocyclichydrogelsstimuli-responsiveswelling of gels

Identifiers

PMID30674789
PMCPMC6318685

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.