ArticleProceedings of the National Academy of Sciences of the United States of America2019
One-megadalton metalloenzyme complex in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- A tungsten-specific maturation pathway governs cofactor assembly of a COThe Journal of biological chemistry · 2026Article
- Classification of tungsten-containing oxidoreductases provides insights into their biochemical and physiological diversity.Frontiers in microbiology · 2026Article
- Obligately Tungsten-Dependent Enzymes─Catalytic Mechanisms, Models and Applications.Biochemistry · 2025Review
- Enzymatic Birch reduction via hydrogen atom transfer at [4Fe-4S]-OHNature communications · 2025Article
- The radical impact of oxygen on prokaryotic evolution-enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third.FEBS letters · 2024Article
- A diversified, widespread microbial gene cluster encodes homologs of methyltransferases involved in methanogenesis.bioRxiv : the preprint server for biology · 2023Article
- Correlated particle transport enables biological free energy transduction.Biophysical journal · 2023Article
- Potential for the anaerobic oxidation of benzene and naphthalene in thermophilic microorganisms from the Guaymas Basin.Frontiers in microbiology · 2023Article
- A Third Way of Energy Conservation in Acetogenic Bacteria.Microbiology spectrum · 2022Article
- Strategies for the Biodegradation of Polyfluorinated Compounds.Microorganisms · 2022Review
- Nothing lasts forever: understanding microbial biodegradation of polyfluorinated compounds and perfluorinated alkyl substances.Microbial biotechnology · 2022Review
- An Abundant and Diverse New Family of Electron Bifurcating Enzymes With a Non-canonical Catalytic Mechanism.Frontiers in microbiology · 2022Article
- Article
- Article
- Dissimilatory sulfate reduction in the archaeon 'Candidatus Vulcanisaeta moutnovskia' sheds light on the evolution of sulfur metabolism.Nature microbiology · 2020Article
- The ever-expanding limits of enzyme catalysis and biodegradation: polyaromatic, polychlorinated, polyfluorinated, and polymeric compounds.The Biochemical journal · 2020Review
- An Aerobic Hybrid Phthalate Degradation Pathway via Phthaloyl-Coenzyme A in Denitrifying Bacteria.Applied and environmental microbiology · 2020Article
- Structural and Functional Characterization of an Electron Transfer Flavoprotein Involved in Toluene Degradation in Strictly Anaerobic Bacteria.Journal of bacteriology · 2019Article
- Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway.Nature communications · 2019Article
- Low potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactors.Nature communications · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reversible biological electron transfer usually occurs between redox couples at standard redox potentials ranging from +0.8 to -0.5 V. Dearomatizing benzoyl-CoA reductases (BCRs), key enzymes of the globally relevant microbial degradation of aromatic compounds at anoxic sites, catalyze a biological Birch reduction beyond the negative limit of this redox window. The structurally characterized BamBC subunits of class II BCRs accomplish benzene ring reduction at an active-site tungsten cofactor; however, the mechanism and components involved in the energetic coupling of endergonic benzene ring reduction have remained hypothetical. We present a 1-MDa, membrane-associated, Bam[(BC)
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.