ArticleProceedings of the National Academy of Sciences of the United States of America2019
Litters of self-replicating origami cross-tiles.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Cooperativity, entropy, and effective concentration in DNA origami self-replication.Science advances · 2026Article
- An enzyme-based approach for highly efficient self-replication of DNA origami dimers.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Design principles, growth laws, and competition of minimal autocatalysts.Communications chemistry · 2024Article
- Proliferating active matter.Nature reviews. Physics · 2023Review
- Recent Advances in DNA Origami-Engineered Nanomaterials and Applications.Chemical reviews · 2023Review
- Direct visualization of floppy two-dimensional DNA origami using cryogenic electron microscopy.iScience · 2022Article
- Mutations in artificial self-replicating tiles: A step toward Darwinian evolution.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Design Approaches and Computational Tools for DNA Nanostructures.IEEE open journal of nanotechnology · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Self-replication and exponential growth are ubiquitous in nature but until recently there were few examples of artificial self-replication. Often replication is a templated process where a parent produces a single offspring, doubling the population in each generation. Many species however produce more than one offspring at a time, enabling faster population growth and higher probability of species perpetuation. We have made a system of cross-shaped origami tiles that yields a number of offspring, four to eight or more, depending on the concentration of monomer units to be assembled. The parent dimer template serves as a seed to crystallize a one-dimensional crystal, a ladder. The ladder rungs are then UV-cross-linked and the offspring are then released by heating, to yield a litter of autonomous daughters. In the complement study, we also optimize the growth conditions to speed up the process and yield a 10
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