SynthesisDiabetes2019
Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes.
Open access · bronzeAbstract readMeta-Analysis
In one paragraph
Synthesis in Diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Genome-wide characterization of 54 urinary metabolites reveals molecular impact of kidney function.Nature communications · 2025Pooled it
- Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease.Nature communications · 2022Pooled it
- Genome-wide search for genes affecting the age at diagnosis of type 1 diabetes.Journal of internal medicine · 2021Pooled it
- Cumulative exposures to glycaemia and lipids are associated with coronary artery disease in type 1 diabetes: a call for action.Cardiovascular diabetology · 2025Article
- Type 1 Diabetes Genetic Risk Scores: History, Application and Future Directions.Current diabetes reports · 2025Review
- Online diabetes self-management education application for reducing glycated hemoglobin level among patients with type 1 diabetes mellitus: a systematic review and meta-analysis.Clinical diabetes and endocrinology · 2024Review
- Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrations.Genome medicine · 2022Article
- Heterogeneous long-term trajectories of glycaemic control in type 1 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2021Article
- Novel Linkage Peaks Discovered for Diabetic Nephropathy in Individuals With Type 1 Diabetes.Diabetes · 2021Article
- Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy.Journal of the American Society of Nephrology : JASN · 2020Article
- Article
- A Genome-Wide Association Study Identifies Blood Disorder-Related Variants Influencing Hemoglobin ADiabetes care · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 7 institutions in 4 countries.
Anna SyreeniFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.
Niina SandholmFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.ORCID 0000-0003-4322-6942
Jingjing CaoProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Iiro ToppilaFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.
David M MaahsDivision of Endocrinology and Diabetes, Stanford Diabetes Research Center, Stanford University School of Medicine, Stanford, CA.
Marian J RewersBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.
Janet K Snell-BergeonBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.
Tina CostacouDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.ORCID 0000-0001-9303-3810
Trevor J OrchardDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
M Luiza CaramoriDivision of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Minnesota, Minneapolis, MN.
Michael MauerDepartments of Pediatrics and Medicine, University of Minnesota, Minneapolis, MN.
Barbara E K KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.ORCID 0000-0003-2379-976X
Ronald KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI.ORCID 0000-0002-4428-6237
Erkka ValoFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.
Maija ParkkonenFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.
Carol ForsblomFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.
Valma HarjutsaloFolkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.ORCID 0000-0003-3568-9779
Andrew D PatersonProgram in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
DCCT/EDIC Research Group
Per-Henrik Groop
FinnDiane Study Group
University of Helsinki · FIHospital for Sick Children · CAUniversity of Colorado Anschutz Medical Campus · USUniversity of Minnesota · USUniversity of Pittsburgh · USUniversity of Wisconsin–Madison · USStanford University · US
Funding
ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI ALBERT, RICHARD K · 1985 to 2008
$52.6MColorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0MVector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4MYOUTH DRUG ABUSE, ADHD, AND RELATED DISRUPTIVE DISORDERSM01RR000400 · NCRR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI KOTLYAR, MICHAEL · 1985 to 2009
$33.7MPILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6MStanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5MRenin Angiotensin System Blockage-DN (RASS)R01DK051975 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MAUER, S MICHAEL · 1997 to 2007
$7.0MSUBCLINICAL HEART DISEASE IN INSULIN-DEPENDENT DIABETESR01HL061753 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J. · 1999 to 2007
$5.2MComplications and Comorbidities of Type 1 DiabetesR01HL113029 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SNELL-BERGEON, JANET KATHLEEN · 2013 to 2016
$2.9MDeterminants of Accelerated CVD in Type 1 DiabetesR01HL079611 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J. · 2004 to 2007
$2.3MNCATS NIH HHS UL1 TR001082NCRR NIH HHS M01 RR000051NCRR NIH HHS M01 RR000400NHLBI NIH HHS R01 HL061753NHLBI NIH HHS R01 HL079611NHLBI NIH HHS R01 HL113029NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30 DK116074NIDDK NIH HHS R01 DK051975
Abstract
Glycated hemoglobin (HbA
Indexed as
Blood GlucoseDiabetes ComplicationsDiabetes Mellitus, Type 1FemaleGenome-Wide Association StudyGlycated HemoglobinHumansMaleBlood GlucoseGlycated Hemoglobin
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.