Evidence map›Paper›PMID 30674578›Full record

ArticleJournal of clinical microbiology2019

Retrospective Analysis of False-Positive and Disputed Rifampin Resistance Xpert MTB/RIF Assay Results in Clinical Samples from a Referral Hospital in Hunan, China.

Peilei Hu, Hongtai Zhang, Joy Fleming, Guofeng Zhu, Shuai Zhang, Yaguo Wang, Fengping Liu, Songlin Yi, Zhongnan Chen, Zhenhua Chen and 7 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Discordance between genotypic and phenotypic methods for the detection of rifampicin and isoniazid resistantJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  4. Article
  5. Association between mutations in aEmerging microbes & infections · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Detection ofInfection and drug resistance · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. False detection of rifampicin resistance using XpertJAC-antimicrobial resistance · 2021
    Article
  15. DisputedAntimicrobial agents and chemotherapy · 2021
    Article
  16. Experimental and therapeutic medicine · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Peilei HuKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Hongtai ZhangKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Joy FlemingKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Guofeng ZhuKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Shuai ZhangKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Yaguo WangKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Fengping LiuClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Songlin YiClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Zhongnan ChenClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Zhenhua ChenClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Binbin LiuClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Daofang GongClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Li WanKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xingyun WangKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Yunhong TanClinical Laboratory, Hunan Chest Hospital, Changsha, China.
Liqiong BaiClinical Laboratory, Hunan Chest Hospital, Changsha, China liqiong99@126.com blj@sun5.ibp.ac.cn.
Lijun BiKey Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China liqiong99@126.com blj@sun5.ibp.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Concerns about the specificity of the Xpert MTB/RIF (Xpert) assay have arisen, as false-positive errors in the determination of

Indexed as

AdolescentAdultAgedAntitubercular AgentsChinaFalse Positive ReactionsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMolecular Diagnostic TechniquesMutationMycobacterium tuberculosisReagent Kits, DiagnosticReferral and ConsultationAntitubercular AgentsReagent Kits, DiagnosticRifampindisputed rifampin resistancerpoB mutationtreatment outcomeXpert MTB/RIF

Identifiers

PMID30674578
PMCPMC6440781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.