Evidence map›Paper›PMID 30674530›Full record

ArticleCancer research2019

Pauline J Beckmann, Jon D Larson, Alex T Larsson, Jason P Ostergaard, Sandra Wagner, Eric P Rahrmann, Ghaidan A Shamsan, George M Otto, Rory L Williams, Jun Wang and 23 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  9. Aggressive Malignant Ossifying Fibromyxoid Tumor With a RareInternational journal of surgical pathology · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. TheInternational journal of molecular sciences · 2024
    Article
  17. Article
  18. Article
  19. Ambra1 in cancer: implications for clinical oncology.Apoptosis : an international journal on programmed cell death · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 13 institutions in 4 countries.

Pauline J BeckmannMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Jon D LarsonMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Alex T LarssonMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Jason P OstergaardMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Sandra WagnerMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Eric P RahrmannMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-2369-0342
Ghaidan A ShamsanDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-0884-7540
George M OttoMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Rory L WilliamsMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-2605-5790
Jun WangTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Catherine LeeTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
Barbara R TschidaMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Paramita DasMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Adrian M DubucDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Branden S MoriarityMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Daniel PicardDepartment of Pediatric Neuro-Oncogenomics, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.ORCID 0000-0003-3375-6202
Xiaochong WuDivision of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, Ontario, Canada.
Fausto J RodriguezDivision of Neuropathology, Johns Hopkins Hospital, Baltimore, Maryland.
Quincy RosemarieMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-0394-1573
Ryan D KrebsMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Amy M MolanMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Addison M DemerMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Michelle M FreesMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Anthony E RizzardiDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Stephen C SchmechelDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Charles G EberhartDepartment of Pathology, Ophthalmology and Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Robert B JenkinsDepartment of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, 200 First Street Southwest, Rochester, Minnesota.
Robert J Wechsler-ReyaTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
David J OddeDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota.
Annie HuangDivision of Hematology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Michael D TaylorDivision of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, Ontario, Canada.
Aaron L SarverMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
David A LargaespadaMasonic Cancer Center, Department of Pediatrics, and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota. larga002@umn.edu.
University of Minnesota Medical Center · USUniversity of Minnesota · USDiscovery Institute · USBrain Tumour Research · GBBrigham and Women's Hospital · USCalifornia Institute of Technology · USCancer Research UK Cambridge Center · GBGerman Cancer Research Center · DEHospital for Sick Children · CAJohns Hopkins Hospital · USJohns Hopkins University · USMayo Clinic · USUniversity of Wisconsin–Madison · US

Funding

TRAINING GRANT IN MICROBIOLOGY/CANCER RESEARCHT32CA009138 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Scott M. Dehm · 1985 to 2026
$11.3M
Project 2: Cell Migration in Mechanically Complex MicroenvironmentsU54CA210190 · NCI · UNIVERSITY OF MINNESOTA · PI WOOD, DAVID KEVIN · 2016 to 2020
$10.0M
Minnesota Training Program in VirologyT32AI083196 · NIAID · UNIVERSITY OF MINNESOTA · PI Louis M Mansky · 2010 to 2026
$3.2M
Sleeping Beauty for uncovering cancer genes in miceR01CA113636 · NCI · UNIVERSITY OF MINNESOTA · PI LARGAESPADA, DAVID ANDREW · 2006 to 2016
$2.5M
Modeling and microsystems approach to glioma invasionR01CA172986 · NCI · UNIVERSITY OF MINNESOTA · PI ODDE, DAVID J., ROSENFELD, STEVEN S · 2013 to 2017
$2.3M
Stem Cell Biology Training ProgramT32GM113846 · NIGMS · UNIVERSITY OF MINNESOTA · PI PERLINGEIRO, RITA C. R. · 2015 to 2019
$712k
Bioinformatics approaches to solve the "Missing Driver" problem in solid tumorsR50CA211249 · NCI · UNIVERSITY OF MINNESOTA · PI SARVER, AARON L · 2016 to 2020
$565k
NCI NIH HHS R01 CA113636NCI NIH HHS R01 CA172986NCI NIH HHS R50 CA211249NCI NIH HHS T32 CA009138NCI NIH HHS U54 CA210190NIAID NIH HHS T32 AI083196NIGMS NIH HHS T32 GM113846
6 · The paper itself

Abstract

Medulloblastoma and central nervous system primitive neuroectodermal tumors (CNS-PNET) are aggressive, poorly differentiated brain tumors with limited effective therapies. Using

Indexed as

AnimalsBrain NeoplasmsCell Transformation, NeoplasticCerebellar NeoplasmsDNA Transposable ElementsFemaleForkhead Transcription FactorsGTPase-Activating ProteinsHumansMaleMedulloblastomaMembrane ProteinsMiceMice, NudeMutagenesis, InsertionalNeural Stem CellsARHGAP36 protein, humanDNA Transposable ElementsForkhead Transcription FactorsFOXR2 protein, humanFoxr2 protein, mouseGTPase-Activating ProteinsMEGF10, humanMegf10 protein, mouseMembrane Proteins

Identifiers

PMID30674530
PMCPMC6397665
OpenAlexW2912167963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.