Evidence map›Paper›PMID 30674445›Full record

ArticleSexual medicine2019

Diabetes Is a Risk Factor for Inflatable Penile Prosthesis Infection: Analysis of a Large Statewide Database.

Michael J Lipsky, Ifeanyi Onyeji, Ron Golan, Ricardo Munarriz, James A Kashanian, Doron S Stember, Peter J Stahl

Open access · goldAbstract read
In one paragraph

Article in Sexual medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Risky business: penile prosthesis in high-risk patients.Translational andrology and urology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Prevention of Penile Prosthesis Infection.Current urology reports · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Michael J LipskyDepartment of Urology, New York Presbyterian Hospital/ Columbia University Medical Center, New York, NY, USA. Electronic address: mjl2114@cumc.columbia.edu.
Ifeanyi OnyejiDepartment of Urology, New York Presbyterian Hospital/ Columbia University Medical Center, New York, NY, USA.
Ron GolanDepartment of Urology, New York Presbyterian Hospital/ Weill Cornell Medical Center, New York, NY, USA.
Ricardo MunarrizCenter for Sexual Medicine, Boston University School of Medicine, Department of Urology, Boston, MA, USA.
James A KashanianDepartment of Urology, New York Presbyterian Hospital/ Weill Cornell Medical Center, New York, NY, USA.
Doron S StemberDepartment of Urology, Mount Sinai Hospital, New York, NY, USA.
Peter J StahlDepartment of Urology, New York Presbyterian Hospital/ Columbia University Medical Center, New York, NY, USA.
New York Hospital Queens · USBoston University · USColumbia University Irving Medical Center · USMount Sinai Hospital · USNewYork–Presbyterian Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough diabetes mellitus (DM) is often discussed as a risk factor for inflatable penile prosthesis (IPP) infection, the link between DM diagnosis and IPP infection remains controversial. High-quality population-based data linking DM to an increased risk of IPP infection have not been published.

aimTo evaluate the association of DM with IPP infection in a large public New York state database.

methodsThe New York Statewide Planning and Research Cooperative System (SPARCS) database was queried for men who underwent initial IPP insertion from 1995-2014. Diabetic patients were identified using ICD-9-CM codes. Patients presenting for first operation with diagnosis or Current Procedural Terminology codes suggestive of prior IPP surgery were excluded. Chi-squared analyses were performed to compare infection rates in diabetics and non-diabetics within the pre- and postantibiotic impregnated eras. Multivariate Cox proportional hazards models were constructed to evaluate whether or not DM was independently associated with IPP infection in the time periods before (1995-2003) and after (2004-2014) the widespread availability of antibiotic impregnated penile prostheses.

main outcome measureTime to prosthesis infection was measured.

results14,969 patients underwent initial IPP insertion during the study period. The overall infection rate was 343/14,969 (2.3%). Infections occurred at a median 3.9 months after implant (interquartile ratio: 1.0-25.0 months). Infectious complications were experienced by 3% (133/4,478) of diabetic patients and 2% (210/10,491) of non-diabetic patients (P < .001). Diabetes was associated with a significantly increased IPP infection risk on multivariable analysis controlling for age, race, comorbidities, insurance status, annual surgeon volume, and era of implantation (Hazard Ratio: 1.32, 95% CI: 1.05-1.66, P = .016).

conclusionOur analysis supports the notion that DM is a risk factor for IPP infection. This has important implications for patient selection and counseling, and raises the question of whether this increased risk can be mitigated by optimization of glycemic control before surgery. Lipsky MJ, Onyeji I, Golan R, et al. Diabetes Is a Risk Factor for Inflatable Penile Prosthesis Infection: Analysis of a Large Statewide Database. Sex Med 2019;7:35-40.

Indexed as

DiabetesErectile DysfunctionInfectionIPPPenile Implant

Identifiers

PMID30674445
PMCPMC6377380
OpenAlexW2914011597

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.