SynthesisBMC nephrology2019
Pregnancy outcomes in women with kidney transplant: Metaanalysis and systematic review.
Synthesis in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07291258 (Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant), which is not on this map. Cited by 86 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant
Who cites it
86 citing papers in PubMed, 7 syntheses or guidelines pooled it, 204 citations in OpenAlex.
- Long-term impact of pregnancy on mortality and graft outcomes in kidney transplant recipients: a systematic review and meta-analysis.International urology and nephrology · 2025Pooled it
- Pregnancy occurring in AA amyloidosis: a series of 27 patients including 3 new French cases.Journal of nephrology · 2024Pooled it
- Adverse Pregnancy Outcomes in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Thoracic organ transplantation and pregnancy outcomes: systematic review and meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Systematic review of pregnancy and renal outcomes for women with chronic kidney disease receiving assisted reproductive therapy.Journal of nephrology · 2022Pooled it
- Follow-Up of Offspring Born to Parents With a Solid Organ Transplantation: A Systematic Review.Transplant international : official journal of the European Society for Organ Transplantation · 2022Pooled it
- Pregnancy outcomes in renal transplant recipients: A systematic review and meta-analysis.Women's health (London, England)Pooled it
- Observational
- Review
- Pregnancy in Patients With Renal Transplant.O&G open · 2026Review
- A Comparison of Pregnancy Outcomes in Women Receiving Intensive Hemodialysis Versus Kidney Transplant Recipients.Kidney international reports · 2026Article
- Article
- Intensive Hemodialysis Versus Kidney Transplantation: Is there Equipoise Regarding Optimal Pregnancy Management?Kidney international reports · 2026Article
- Outcomes and management strategies of pregnancies after heart and lung transplantation across Europe.JHLT open · 2026Article
- Safety profiles of cyclosporine and tacrolimus in pregnancy: a pharmacovigilance analysis using the FDA Adverse Event Reporting System.Frontiers in medicine · 2026Article
- Pregnancy Outcomes Using Assisted Reproductive Technology in Kidney Transplant Recipients.Transplantation · 2025Article
- Beyond the first pregnancy: learning from the history of a kidney transplant recipient who experienced five pregnancies.Journal of nephrology · 2025Article
- Kidney and Pregnancy: A Comprehensive Review.Clinics and practice · 2025Review
- Kidney health outcomes of hypertensive disorders of pregnancy.Nature reviews. Nephrology · 2025Review
- Pregnancy After Solid Organ Transplantation: Review of the Evidence and Recommendations.Transplantation · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReproductive function in women with end stage renal disease generally improves after kidney transplant. However, pregnancy remains challenging due to the risk of adverse clinical outcomes.
methodsWe searched PubMed/MEDLINE, Elsevier EMBASE, Scopus, BIOSIS Previews, ISI Science Citation Index Expanded, and the Cochrane Central Register of Controlled Trials from date of inception through August 2017 for studies reporting pregnancy with kidney transplant.
resultsOf 1343 unique studies, 87 met inclusion criteria, representing 6712 pregnancies in 4174 kidney transplant recipients. Mean maternal age was 29.6 ± 2.4 years. The live-birth rate was 72.9% (95% CI, 70.0-75.6). The rate of other pregnancy outcomes was as follows: induced abortions (12.4%; 95% CI, 10.4-14.7), miscarriages (15.4%; 95% CI, 13.8-17.2), stillbirths (5.1%; 95% CI, 4.0-6.5), ectopic pregnancies (2.4%; 95% CI, 1.5-3.7), preeclampsia (21.5%; 95% CI, 18.5-24.9), gestational diabetes (5.7%; 95% CI, 3.7-8.9), pregnancy induced hypertension (24.1%; 95% CI, 18.1-31.5), cesarean section (62.6, 95% CI 57.6-67.3), and preterm delivery was 43.1% (95% CI, 38.7-47.6). Mean gestational age was 34.9 weeks, and mean birth weight was 2470 g. The 2-3-year interval following kidney transplant had higher neonatal mortality, and lower rates of live births as compared to > 3 year, and < 2-year interval. The rate of spontaneous abortion was higher in women with mean maternal age < 25 years and > 35 years as compared to women aged 25-34 years.
conclusionAlthough the outcome of live births is favorable, the risks of maternal and fetal complications are high in kidney transplant recipients and should be considered in patient counseling and clinical decision making.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.