Evidence map›Paper›PMID 30674162›Full record

ReviewGels (Basel, Switzerland)2015

New Formulations of Polysaccharide-Based Hydrogels for Drug Release and Tissue Engineering.

Francesca Camponeschi, Andrea Atrei, Giulia Rocchigiani, Lorenzo Mencuccini, Marianna Uva, Rolando Barbucci

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesca CamponeschiDepartment of Biotechnology, Chemistry and Pharmacy of University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. camponeschi@unisi.it.
Andrea AtreiDepartment of Biotechnology, Chemistry and Pharmacy of University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. atrei@unisi.it.
Giulia RocchigianiDepartment of Biotechnology, Chemistry and Pharmacy of University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. giulia.rocchigiani@hotmail.it.
Lorenzo MencucciniDepartment of Biotechnology, Chemistry and Pharmacy of University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. lorenzo.mencuccini@unisi.it.
Marianna UvaDepartment of Biotechnology, Chemistry and Pharmacy of University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. marianna.uva@unisi.it.
Rolando BarbucciInteruniversity Research Centre for Advanced Medical Systems (C.R.I.S.M.A.), Viale Giacomo Matteotti 15/16, 53034 Colle di Val d'Elsa, Italy. rolando.barbucci@unisi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polysaccharide-based hydrogels are very promising materials for a wide range of medical applications, ranging from tissue engineering to controlled drug delivery for local therapy. The most interesting property of this class of materials is the ability to be injected without any alteration of their chemical, mechanical and biological properties, by taking advantage of their thixotropic behavior. It is possible to modulate the rheological and chemical-physical properties of polysaccharide hydrogels by varying the cross-linking agents and exploiting their thixotropic behavior. We present here an overview of our synthetic strategies and applications of innovative polysaccharide-based hydrogels: hyaluronan-based hydrogel and new derivatives of carboxymethylcellulose have been used as matrices in the field of tissue engineering; while guar gum-based hydrogel and hybrid magnetic hydrogels, have been used as promising systems for targeted controlled drug release. Moreover, a new class of materials, interpenetrating hydrogels (IPH), have been obtained by mixing various native thixotropic hydrogels.

Indexed as

drug deliveryinjectable hydrogelsmagnetic nanoparticlespolysaccharide-based hydrogelsthixotropytissue engineering

Identifiers

PMID30674162
PMCPMC6318688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.