Evidence map›Paper›PMID 30674087›Full record

ArticleTropical medicine & international health : TM & IH2019

Population coverage and factors associated with participation following a mass drug administration of azithromycin for trachoma elimination in Amhara, Ethiopia.

Caleb D Ebert, Tigist Astale, Eshetu Sata, Mulat Zerihun, Andrew W Nute, Aisha E P Stewart, Demelash Gessese, Gedefaw Ayenew, Zebene Ayele, Berhanu Melak and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Caleb D EbertDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Tigist AstaleTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Eshetu SataTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Mulat ZerihunTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Andrew W NuteTrachoma Control Program, The Carter Center, Atlanta, GA, USA.
Aisha E P StewartTrachoma Control Program, The Carter Center, Atlanta, GA, USA.
Demelash GesseseTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Gedefaw AyenewTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Zebene AyeleTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Berhanu MelakTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
Melsew ChanyalewHealth Promotion and Disease Prevention Core Process, The Amhara Regional Health Bureau, Bahir Dar, Ethiopia.
Bizuayehu GashawDirectorate, The Amhara Regional Health Bureau, Bahir Dar, Ethiopia.
Zerihun TadesseTrachoma Control Program, The Carter Center, Addis Ababa, Ethiopia.
E Kelly CallahanTrachoma Control Program, The Carter Center, Atlanta, GA, USA.
Samuel M JennessDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Scott D NashTrachoma Control Program, The Carter Center, Atlanta, GA, USA.
The Carter Center · ETCarter Center · USAmhara Regional Health Bureau · ETEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMass drug administration (MDA) with azithromycin is a core component of the WHO-recommended strategy to eliminate trachoma as a public health problem, but low participation rates in MDA campaigns may undermine the effectiveness of this intervention. We explored factors associated with individual MDA participation at the individual, head of household and household levels in Amhara, Ethiopia.

methodsWe conducted four district-level, multilevel cluster random coverage surveys to collect data on self-reported MDA participation and predictors. Random-effects logistic regression modelling was used to identify correlates of MDA participation while adjusting for nesting of individuals at the household and village level.

resultsThe district-level self-reported participation in the trachoma MDA ranged from 78.5% to 86.9%. Excellent and fair health status (Odds ratio [OR] = 5.77; 95% Confidence interval [CI]: 3.04, 10.95; OR = 7.08; 95% CI: 3.47, 14.46), advanced knowledge of the MDA campaign (OR = 2.93; 95% CI: 2.04, 4.21) and knowledge of trachoma (OR = 1.60; 95% CI: 1.17, 2.19) were all positively associated with MDA participation. When excluding heads of household from the model, correlates retained similar positive associations to participation, in addition to the head of household participation (OR = 3.34; 95% CI: 2.46, 4.54).

conclusionsTo increase the impact of MDA campaigns, MDA mobilisation strategies-including comprehensive trachoma and azithromycin messaging and MDA campaign awareness-should target heads of household, those in poorer health and older age groups.

Indexed as

CommunicationHealth Knowledge, Attitudes, PracticeMass Drug AdministrationPatient Acceptance of Health CareAdolescentAdultAgedAnti-Bacterial AgentsAwarenessAzithromycinChildChild, PreschoolEthiopiaFamily CharacteristicsFemaleHealth StatusAnti-Bacterial AgentsAzithromycinadministration en masse de médicamentscoverage surveyethiopiaEthiopiemass drug administrationSAFE strategystratégie SAFEsurveillance de la couverturetrachomatrachome

Identifiers

PMID30674087
PMCPMC6850572
OpenAlexW2914507584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.