Evidence map›Paper›PMID 30673882›Full record

ReviewCurrent infectious disease reports2019

Clostridioides difficile-Associated Diarrhea: Infection Prevention Unknowns and Evolving Risk Reduction Strategies.

Michelle Doll, Michele Fleming, Michael P Stevens, Gonzalo Bearman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current infectious disease reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Clostridioides difficile Near-Patient Testing Versus Centralized Testing: A Pragmatic Cluster Randomized Crossover Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Trial
  2. Influence of Antibiotic Exposure Intensity on the Risk of Clostridioides difficile Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  3. Estimating the effect of active detection and isolation onInfection control and hospital epidemiology · 2023
    Article
  4. Volatilomes of Bacterial Infections in Humans.Frontiers in neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michelle DollVirginia Commonwealth University Medical Center, 1300 E. Marshall Street, Richmond, VA, 23298-0019, USA. Michelle.doll@vcuhealth.org.
Michele FlemingVirginia Commonwealth University Medical Center, 1300 E. Marshall Street, Richmond, VA, 23298-0019, USA.
Michael P StevensVirginia Commonwealth University Medical Center, 1300 E. Marshall Street, Richmond, VA, 23298-0019, USA.
Gonzalo BearmanVirginia Commonwealth University Medical Center, 1300 E. Marshall Street, Richmond, VA, 23298-0019, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewNew controversies in the diagnosis and prevention of Clostridiodes difficile are challenging and at times changing infection control practice at many medical centers. RECENT

findingsMolecular epidemiologic studies are changing our understanding of C. difficile and its spectrum of disease. C. difficile as a hospital-acquired infection is likely largely overdiagnosed given overly sensitive molecular testing and widespread colonization of ill or debilitated patients. Clostridiodes difficile infection continues to challenge infection prevention programs. Shifts in our understanding of the epidemiology of this organism and its spectrum of clinical presentations are changing the approach to prevention efforts. Nevertheless, cleanliness of the healthcare environment and antimicrobial stewardship remain core risk reduction strategies. Other strategies such as screening and isolation are inciting controversy. The optimal infection prevention strategies for C. difficile remain the subject of intense study and debate.

Indexed as

Antibiotic stewardshipC. difficileClostridiodes difficileDiagnostic stewardshipInfection prevention

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.