Evidence map›Paper›PMID 30673834›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019

Factors affecting epilepsy prognosis in patients with tuberous sclerosis.

Gülen Gül Mert, Şakir Altunbaşak, Özlem Hergüner, Faruk İncecik, Hilal Cansever Övetti, Neslihan Özcan, Duygu Kuşçu, İlker Ünal

Abstract read
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gülen Gül MertDepartment of Pediatrics, Division of Pediatric Neurology, Cukurova University, Adana, Turkey. dr_gulen@hotmail.com.
Şakir AltunbaşakDepartment of Pediatrics, Division of Pediatric Neurology, Cukurova University, Adana, Turkey.
Özlem HergünerDepartment of Pediatrics, Division of Pediatric Neurology, Cukurova University, Adana, Turkey.
Faruk İncecikDepartment of Pediatrics, Division of Pediatric Neurology, Cukurova University, Adana, Turkey.
Hilal Cansever ÖvettiDepartment of Pediatrics, Division of Pediatric Neurology, Cukurova University, Adana, Turkey.
Neslihan ÖzcanDepartment of Pediatrics, Division of Pediatric Neurology, Cukurova University, Adana, Turkey.
Duygu KuşçuDepartment of Psychology, Cukurova University, Adana, Turkey.
İlker ÜnalDepartment of Biostatistics, Cukurova University, Adana, Turkey.
Cukurova University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to determine the characteristics of epileptic seizures that significantly affect the cognitive functions of 83 patients followed with tuberous sclerosis complex (TSC), their resistance to treatment and risk factors causing this resistance. MATERIALS-

methodsIn order to determine the prognosis, the seizure-free/seizure-controlled group and the group with refractory seizures were compared. In addition, risk factors affecting cognitive functions in the patients were determined.

resultsThere was a statistical significance between the presence of a history of seizures in the neonatal period, the age of onset of seizures being less than 2 years of age, autism, status epilepticus, Lennox-Gastaut syndrome (LGS), presence of infantile spasm, generalization of the electroencephalography (EEG) findings, the number of tubers in cerebral imaging being more than three and refractory seizures (p < 0.05). Statistically significant relationship was found between presence of a history of seizures in the neonatal period, the age of onset of seizures, autism, LGS, presence of infantile spasm, presence of status epilepticus history, history of using more than three antiepileptic drugs, generalization of EEG findings, presence of SEGA in cerebral imaging, number of tubers being more than three and the patient's mental retardation (p < 0.05).

conclusionIn logistic regression analysis, the age of the seizure onset being less than 2 years of age, the presence of autism and number of tubers being more than three in cerebral magnetic resonance imaging (MRI) are determined to be the risk factors that most likely to increase the seizures to be more resistant.

Indexed as

AdolescentAge of OnsetChildChild, PreschoolDrug Resistant EpilepsyFemaleHumansInfantMalePrognosisRisk FactorsTuberous SclerosisEpilepsyPrognosisTuberous sclerosis

Identifiers

PMID30673834
OpenAlexW2914694598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.