ArticleHeart and vessels2019
New insight into the intraventricular pressure gradient as a sensitive indicator of diastolic cardiac dysfunction in patients with childhood cancer after anthracycline therapy.
Article in Heart and vessels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The Potential Protective Effects of Resveratrol Against Cabazitaxel-Induced Oxidative Stress and Cardiotoxicity in Rats.Cardiovascular toxicology · 2026Article
- Concomitant changes in regional myocardial deformation and intraventricular pressure gradients in normal and sedated goats: advanced multimodal echocardiographic study.BMC veterinary research · 2025Article
- Intraventricular pressure difference estimation based on blood speckle tracking-invasive validation and early clinical application.European heart journal. Cardiovascular Imaging · 2025Article
- Summary Concerning 16 Years of Research Activities in the Department of Pediatrics at Juntendo University.Juntendo medical journal · 2025Article
- Isovolumic relaxation intraventricular pressure difference predicts elevated left ventricular end-diastolic pressure in patients with coronary artery disease.Scientific reports · 2024Article
- Sensitive detection of hemodynamic changes after fetoscopic laser photocoagulation by assessing intraventricular pressure difference in fetuses with twin-to-twin transfusion syndrome.Journal of perinatal medicine · 2024Article
- Assessment of anthracycline-induced cardiotoxicity in childhood cancer survivors during long-term follow-up using strain analysis and intraventricular pressure gradient measurements.Heart and vessels · 2024Article
- Non-Invasive Assessment of the Intraventricular Pressure Using Novel Color M-Mode Echocardiography in Animal Studies: Current Status and Future Perspectives in Veterinary Medicine.Animals : an open access journal from MDPI · 2023Review
- Prevalence of Diastolic Dysfunction in Adult Survivors of Childhood Cancer: A Report From SJLIFE Cohort.JACC. CardioOncology · 2023Article
- Heart Failure with Preserved Ejection Fraction in Children.Pediatric cardiology · 2023Review
- Intraventricular pressure gradient: A novel tool to assess the post-infarction chronic congestive heart failure.Frontiers in cardiovascular medicine · 2022Article
- Novel color M-mode echocardiography for non-invasive assessment of the intraventricular pressure in goats: Feasibility, repeatability, and the effect of sedation.Frontiers in veterinary science · 2022Article
- Color M-Mode Echocardiography for Non-Invasive Assessment of the Intraventricular Pressure in Dogs Before and After Ductus Arteriosus Occlusion: A Retrospective Study.Frontiers in veterinary science · 2022Article
- Left ventricular diastolic pressure gradient and outcome in advanced chronic kidney disease patients with preserved ejection fraction.The international journal of cardiovascular imaging · 2021Article
- Effect of Loading Changes on the Intraventricular Pressure Measured by Color M-Mode Echocardiography in Rats.Diagnostics (Basel, Switzerland) · 2021Article
- The Utility of Intraventricular Pressure Gradient for Early Detection of Chemotherapy-Induced Subclinical Cardiac Dysfunction in Dogs.Animals : an open access journal from MDPI · 2021Article
- Assessment of left-ventricular diastolic function in pediatric intensive-care patients: a review of parameters and indications compared with those for adults.World journal of pediatrics : WJP · 2021Review
- Key factors of diastolic dysfunction and abnormal left ventricular relaxation in diabetic rats.Journal of medical ultrasonics (2001) · 2020Article
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Authors and funding
12 authors.
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Abstract
Cardiac dysfunction due to cardiotoxicity from anthracycline chemotherapy is a leading cause of morbidity and mortality in survivors of childhood cancer. The intraventricular pressure gradient (IVPG) of the left ventricle (LV) is the suction force of blood from the left atrium to the LV apex during early diastole and is a sensitive indicator of diastolic function. We assessed IVPG as a new indicator of the cardiac dysfunction in survivors of childhood cancer after anthracycline therapy. We performed a prospective echocardiographic study on 40 survivors of childhood cancer aged 6-26 years who received anthracycline therapy (group A) and 53 similar-age normal controls (group N). The subjects were divided into the younger groups, N1 and A1 (age < 16 years); older groups, N2 and A2 (age ≥ 16 years). IVPG was calculated using color M-mode Doppler imaging of the mitral inflow using Euler's equation. Total IVPG was divided into the basal and mid-to-apical IVPG to demonstrate more clearly the mechanisms of the LV diastolic suction force. The total anthracycline dose was 16.2-600.0 mg/m
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