Evidence map›Paper›PMID 30672499›Full record

ArticleIndian journal of ophthalmology2019

Macular toxicity after short-term hydroxychloroquine therapy.

Isil Pasaoglu, Funda E Onmez

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Factors associated with early hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  5. Article
  6. Accelerated hydroxychloroquine toxic retinopathy.Documenta ophthalmologica. Advances in ophthalmology · 2024
    Article
  7. Article
  8. Review
  9. Hydroxychloroquine and ritonavir for COVID-19 infection: a possible synergic toxicity for retinal pigmented epithelium.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Isil PasaogluDepartment of Neuro-Ophthalmology, Beyoglu Eye Education and Research Hospital, Istanbul, Turkey.
Funda E OnmezDepartment of Neuro-Ophthalmology, Beyoglu Eye Education and Research Hospital, Istanbul, Turkey.
Istanbul Eye Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an unusual case of hydroxychloroquine (HCQ) toxicity after only 2 months of starting the treatment. A 42-year-old woman presented with visual impairment. Her visual acuity was 20/20 in the right eye and 20/25 in the left eye. Ophthalmologic examination revealed a bull's eye pattern in both eyes which was more prominent in the left eye. She had received HCQ therapy (400 mg/day) for 1 month, and had been taking 200 mg/day for 1 month for the treatment of rheumatoid arthritis. HCQ macular toxicity is rarely seen in short-term use, before 5 years, and to our knowledge, there is only one other case reported in the literature.

Indexed as

Visual AcuityAdultAntirheumatic AgentsArthritis, RheumatoidElectroretinographyFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansHydroxychloroquineMacula LuteaRetinal DiseasesTomography, Optical CoherenceVisual FieldsAntirheumatic AgentsHydroxychloroquineBull's eyehydroxychloroquine therapy

Identifiers

PMID30672499
PMCPMC6376838
OpenAlexW2912583876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.