Evidence map›Paper›PMID 30672171›Full record

ArticleKorean journal of radiology2019

Computed Tomography Pulmonary Angiography during Pregnancy: Radiation Dose of Commonly Used Protocols and the Effect of Scan Length Optimization.

Babs M F Hendriks, Roald S Schnerr, Gianluca Milanese, Cécile R L P N Jeukens, Sandra Niesen, Nienke G Eijsvoogel, Joachim E Wildberger, Marco Das

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Babs M F HendriksDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID 0000-0001-9163-337X
Roald S SchnerrDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Gianluca MilaneseDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Cécile R L P N JeukensDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Sandra NiesenDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Nienke G EijsvoogelDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Joachim E WildbergerDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Marco DasDepartment of Radiology & Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Maastricht University Medical Centre · NLUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the radiation dose for pregnant women and fetuses undergoing commonly used computed tomography of the pulmonary arteries (CTPA) scan protocols and subsequently evaluate the simulated effect of an optimized scan length. MATERIALS AND

methodsA total of 120 CTPA datasets were acquired using four distinctive scan protocols, with 30 patients per protocol. These datasets were mapped to Cristy phantoms in order to simulate pregnancy and to assess the effect of an effective radiation dose (in mSv) in the first, second, or third trimester of pregnancy, including a simulation of fetal dose in second and third trimesters. The investigated scan protocols involved a 64-slice helical scan at 120 kVp, a high-pitch dual source acquisition at 100 kVp, a dual-energy acquisition at 80/140 kVp, and an automated-kV-selection, high pitch helical scan at a reference kV of 100 kV

resultsLarge inter-scanner and inter-protocol variations were found; application of the latest technology decreased the dose for non-pregnant women by 69% (7.0-2.2 mSv). Individual scan length optimization proved safe and effective, decreasing the fetal dose by 76-83%. Nineteen (16%) cases of pulmonary embolism were diagnosed and, after scan length optimization, none were missed.

conclusionCareful CTPA scan protocol selection and additional optimization of scan length may result in significant radiation dose reduction for a pregnant patient and her fetus, whilst maintaining diagnostic confidence.

Indexed as

Computed Tomography AngiographyFemaleFetusHumansLungMiddle AgedPhantoms, ImagingPregnancyPregnancy Complications, CardiovascularPulmonary ArteryPulmonary EmbolismRadiation DosageReproducibility of ResultsTomography, X-Ray ComputedComputed tomographyFetusPregnancyPulmonary angiographyPulmonary embolismRadiation dose

Identifiers

PMID30672171
PMCPMC6342764
OpenAlexW2907044502

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.