ArticleJournal of evolutionary biology2019
Crystal toxins and the volunteer's dilemma in bacteria.
Article in Journal of evolutionary biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Review
- Manipulating multi-level selection in a fungal entomopathogen reveals social conflicts and a method for improving biocontrol traits.PLoS pathogens · 2024Article
- Ecological dependencies and the illusion of cooperation in microbial communities.Microbiology (Reading, England) · 2024Article
- Equilibria and oscillations in cheat-cooperator dynamics.Evolution letters · 2023Article
- The evolution of manipulative cheating.eLife · 2022Article
- Ten recent insights for our understanding of cooperation.Nature ecology & evolution · 2021Review
- Trends in mathematical modeling of host-pathogen interactions.Cellular and molecular life sciences : CMLS · 2020Review
- Crystal toxins and the volunteer's dilemma in bacteria.Journal of evolutionary biology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The growth and virulence of the bacteria Bacillus thuringiensis depend on the production of Cry toxins, which are used to perforate the gut of its host. Successful invasion of the host relies on producing a threshold amount of toxin, after which there is no benefit from producing more toxin. Consequently, the production of Cry toxin appears to be a different type of social problem compared with the public goods scenarios that bacteria usually encounter. We show that selection for toxin production is a volunteer's dilemma. We make specific predictions that (a) selection for toxin production depends upon an interplay between the number of bacterial cells that each host ingests and the genetic relatedness between those cells; (b) cheats that do not produce toxin gain an advantage when at low frequencies, and at high bacterial density, allowing them to be maintained in a population alongside toxin-producing cells. More generally, our results emphasize the diversity of the social games that bacteria play.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.