Evidence map›Paper›PMID 30671895›Full record

Observational studyJournal of clinical monitoring and computing2020

Measuring the accuracy of propofol target-controlled infusion (TCI) before and after surgery with major blood loss.

Thomas Mohler, JoEllen Welter, Martina Steurer, Luis Neumann, Max Zueger, Thomas Kraemer, Alexander Dullenkopf

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of clinical monitoring and computing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Effect of sleep deprivation on general anesthesia in rats.International journal of burns and trauma · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas MohlerInstitute of Anaesthesia and Intensive Care Medicine, Spital Thurgau, Pfaffenholzstrasse 4, 8501, Frauenfeld, Switzerland.
JoEllen WelterInstitute of Anaesthesia and Intensive Care Medicine, Spital Thurgau, Pfaffenholzstrasse 4, 8501, Frauenfeld, Switzerland.
Martina SteurerDepartment of Pediatrics, University of California, San Francisco, USA.
Luis NeumannInstitute of Anaesthesia and Intensive Care Medicine, Spital Thurgau, Pfaffenholzstrasse 4, 8501, Frauenfeld, Switzerland.
Max ZuegerInstitute of Laboratory Medicine, Spital Thurgau, Frauenfeld, Switzerland.
Thomas KraemerForensic Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.
Alexander DullenkopfInstitute of Anaesthesia and Intensive Care Medicine, Spital Thurgau, Pfaffenholzstrasse 4, 8501, Frauenfeld, Switzerland. alexander.dullenkopf@stgag.ch.ORCID http://orcid.org/0000-0002-1456-6457

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Target-controlled infusion (TCI) is based on pharmacokinetic models designed to achieve a desired drug level in the blood. TCI's predictive accuracy of plasma propofol levels at the end of surgery with major blood loss has not been well established. This prospective observational study included adult patients (BMI 20-35 kg/m

Indexed as

Anesthesia, IntravenousInfusions, IntravenousAdultAgedAged, 80 and overAnesthesiaAnesthesia, GeneralAnesthetics, IntravenousArterial PressureElectroencephalographyFemaleHeart RateHemodynamicsHumansInfusion PumpsLactic AcidAnesthetics, IntravenousLactic AcidPropofolAutomated drug delivery devicesPropofol administrationTarget controlled infusion

Identifiers

PMID30671895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.