Evidence map›Paper›PMID 30671669›Full record

ArticleSurgical endoscopy2019

After laparoscopic liver resection for colorectal liver metastases, age does not influence morbi-mortality.

Alban Zarzavadjian Le Bian, Nicolas Tabchouri, Mostefa Bennamoun, Christophe Louvet, Candice Tubbax, Anthony Sarran, Marine Lefevre, Marc Beaussier, Frédéric Pamoukdjian, Philippe Wind and 2 more

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alban Zarzavadjian Le BianDepartment of Digestive Surgery and Surgical Oncology - Avicenne Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris XIII, 125 rue de Stalingrad, 93000, Bobigny, France. spleen2008@live.fr.ORCID 0000-0002-7384-1148
Nicolas TabchouriDepartment of Digestive, Oncological and Metabolic Surgery - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Mostefa BennamounDepartment of Oncology - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Christophe LouvetDepartment of Oncology - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Candice TubbaxDepartment of Oncology - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Anthony SarranDepartment of Radiology and Medical Imaging - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Marine LefevreDepartment of Histopathology, Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Marc BeaussierDepartment of Anesthesiology, Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
Frédéric PamoukdjianDepartment of Geriatric Medicine, Coordination Unit of Geriatric Oncology, Avicenne Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris XIII, 125 rue de Stalingrad, 93000, Bobigny, France.
Philippe WindDepartment of Digestive Surgery and Surgical Oncology - Avicenne Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris XIII, 125 rue de Stalingrad, 93000, Bobigny, France.
Brice GayetDepartment of Digestive, Oncological and Metabolic Surgery - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.
David FuksDepartment of Digestive, Oncological and Metabolic Surgery - Institut Mutualiste Montsouris, 42 Boulevard Jourdan, 75014, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatectomy remains the only curative option in patients presenting with colorectal liver metastases (CLM). Although laparoscopic approach has improved postoperative morbidity and mortality rates, its suitability for patients of all age groups has yet to be confirmed. The aim of this study was to analyze postoperative outcomes following laparoscopic liver resection (LLR) in different age groups of patients presenting with CLM.

methodsAll patients who underwent LLR for CLM from 2008 to 2017 were reviewed. Patients were divided into four age groups: < 55, 55-65 years, 65-75 and > 75 years. Baseline and intraoperative characteristics as well as postoperative morbidity and mortality were compared between all four groups.

resultsOverall, 335 patients were included with 34 (10%), 113 (34%), 136 (41%) and 52 (15%) in < 55, 55-65, 65-75 and > 75 years subgroups. Baseline characteristics were similar between all four groups except for elevated pressure, dyslipidemia and ASA score which were higher in older patients. Regarding surgical procedures, major hepatectomy, uni- or bisegmentectomy and wedge resection were performed in 122 (36%), 87 (26%) and 126 (38%) patients, respectively, with no significant differences between age groups. Overall, 90-day postoperative mortality rate was nil and postoperative morbidity was similar between all four groups except for biliary fistula occurrence, which was higher in < 55 years patients (p = 0.006).

conclusionShort-term postoperative outcome following LLR for CLM does not seem to be affected by age. Curative laparoscopic treatment should therefore be considered whenever possible, regardless of patient age.

Indexed as

AdultAgedAged, 80 and overAge FactorsColorectal NeoplasmsFemaleFranceHepatectomyHumansLaparoscopyLiver NeoplasmsMaleMiddle AgedMorbidityNeoplasm MetastasisPostoperative ComplicationsAgeColorectal metastasisElderlyHepatectomyLaparoscopyLiver resectionMorbi-mortality

Identifiers

PMID30671669

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.