Evidence map›Paper›PMID 30671667›Full record

ArticleSurgical endoscopy2019

Outcome of peroral endoscopic myotomy in children with achalasia.

Zaheer Nabi, Mohan Ramchandani, Radhika Chavan, Santosh Darisetty, Rakesh Kalapala, Upender Shava, Manu Tandan, Rama Kotla, D Nageshwar Reddy

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Achalasia cardia sub-types in children: Does it affect the response to therapy?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Recent advances in third space or intramural endoscopy.World journal of gastrointestinal endoscopy · 2020
    Review
  10. Per-oral endoscopic myotomy and gastroesophageal reflux: Where do we stand after a decade of "POETRY"?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zaheer NabiAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India. zaheernabi1978@gmail.com.ORCID 0000-0003-2713-4781
Mohan RamchandaniAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Radhika ChavanAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Santosh DarisettyAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Rakesh KalapalaAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Upender ShavaAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Manu TandanAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Rama KotlaAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
D Nageshwar ReddyAsian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad, 500 082, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsAchalasia cardia is rare in children and optimum endoscopic management options are not well known. Peroral endoscopic myotomy (POEM) is a novel treatment modality for achalasia with excellent results in adult patients. The long-term outcomes of POEM are not well known in children. In this study, we aim to evaluate the outcome of POEM in children with idiopathic achalasia.

methodsWe analyzed the data of children (≤ 18 years) diagnosed with achalasia from September 2013 to January 2018. Technical success, clinical success, and adverse events were assessed. Post-POEM, gastroesophageal reflux (GER) was assessed with 24-h pH-impedance study and esophagogastroduodenoscopy.

resultsA total of 44 children (boys-23, girls-21) with mean age of 14.5 ± 3.41 years (4-18) were diagnosed with achalasia during the study period. Of these, 43 children underwent POEM. The subtypes of achalasia according to Chicago classification were type I-11, type II-29, type III-2, and unclassified-2. Eighteen children (40.9%) had history of prior treatment. POEM was successfully performed in 43 children (technical success-97.72%). Intra-operative adverse events occurred in 11 (25.6%) children including retroperitoneal CO2 (7), capnoperitoneum (3), and mucosal injury (1). Clinical success at 1, 2, 3, and 4 years' follow-up was 92.8%, 94.4%, 92.3%, and 83.3%, respectively. Erosive esophagitis was detected in 55% (11/20) children. On 24-h pH study, GER was detected in 53.8% (7/13) children.

conclusionPOEM is a safe, effective, and durable treatment for achalasia in children. However, GER is a potential concern and should be evaluated in prospective studies before adopting POEM for the management of achalasia in children.

Indexed as

AdolescentChildChild, PreschoolEsophageal AchalasiaEsophagoscopyFemaleHeller MyotomyHumansMaleMouthNatural Orifice Endoscopic SurgeryRetrospective StudiesTreatment OutcomeAchalasiaChildEndoscopyMyotomy

Identifiers

PMID30671667
OpenAlexW2913464677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.