ArticleJournal of diabetes research2018
Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes.
Article in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Nocturnal heart rate during sleep is associated with increased risk of type 2 diabetes mellitus in adults with obstructive sleep apnoea syndrome.Annals of medicine · 2025Article
- The Triglyceride-Glucose Index Mediates the Association Between Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease: Findings From Two Cross-Sectional Datasets.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Hypoxia-Induced Insulin Resistance Mediates the Elevated Cardiovascular Risk in Patients with Obstructive Sleep Apnea: A Comprehensive Review.Reviews in cardiovascular medicine · 2024Review
- Cardiovascular Disease Outcomes Associated with Obstructive Sleep Apnea in Diabetics: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2023Review
- Investigating the Relationship between Obstructive Sleep Apnoea, Inflammation and Cardio-Metabolic Diseases.International journal of molecular sciences · 2023Review
- Postprandial glucose and HbA1c are associated with severity of obstructive sleep apnoea in non-diabetic obese subjects.Journal of endocrinological investigation · 2021Article
- Compared to Individuals with Mild to Moderate Obstructive Sleep Apnea (OSA), Individuals with Severe OSA Had Higher BMI and Respiratory-Disturbance Scores.Life (Basel, Switzerland) · 2021Article
- Development and validation of a nomogram for predicting the risk of obstructive sleep apnea in patients with type 2 diabetes.Annals of translational medicine · 2020Article
- The Interaction Between Sleep and Metabolism in Alzheimer's Disease: Cause or Consequence of Disease?Frontiers in aging neuroscience · 2019Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsObstructive sleep apnea (OSA) is a very common disorder which is associated with metabolic comorbidities. The aims of this study were to analyze clinical data of patients with OSA and evaluate influence of sleep-disordered breathing on glycometabolism and its underlying mechanisms.
methodsWe designed a cross-sectional study involving 53 OSA patients in The First Hospital of Jilin University from March 2015 to March 2016. They underwent a full-night polysomnography, measurement of fasting blood glucose and blood lipid profiles. Besides, we chose 20 individuals with type 2 diabetes mellitus (T2DM) as a subgroup for an in-depth study. This group additionally underwent a steamed bread meal test and measurement of HbA1c, C-reactive protein, tumor necrosis factor-
resultsThe two groups which with or without T2DM showed no significant differences in baseline characteristics. As for OSA patients with T2DM, the severe OSA group had higher homeostasis model assessment of insulin resistance (HOMA-IR) (
conclusionsOur study showed that sleep-disordered breathing exerted negative influence on glucose metabolisms. The impairment of hypothalamic-pituitary-adrenal axis activity may be one of the underlying mechanisms of the glycometabolic dysfunctions in OSA with T2DM patients.
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