Evidence map›Paper›PMID 30671321›Full record

ArticleGMS infectious diseases2016

Temporal trends of the in vitro activity of tigecycline and comparator antibiotics against clinical aerobic bacterial isolates collected in Germany, 2006-2014: results of the Tigecycline Evaluation and Surveillance Trial (TEST).

Michael Kresken, Barbara Körber-Irrgang, Christian Petrik, Harald Seifert, Arne Rodloff, Karsten Becker

Abstract read
In one paragraph

Article in GMS infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Vancomycin-ResistantAntibiotics (Basel, Switzerland) · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael KreskenAntiinfectives Intelligence GmbH, Rheinbach, Germany.
Barbara Körber-IrrgangAntiinfectives Intelligence GmbH, Rheinbach, Germany.
Christian PetrikPfizer Pharma GmbH, Berlin, Germany.
Harald SeifertUniversity Hospital Cologne, Institute for Medical Microbiology, Immunology and Hygiene, Cologne, Germany.
Arne RodloffUniversity Hospital Leipzig, Institute for Medical Microbiology and Epidemiology of Infectious Diseases, Leipzig, Germany.
Karsten BeckerUniversity Hospital Münster, Institute of Medical Microbiology, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the rapidly changing landscape of antimicrobial resistance, continuous monitoring of antimicrobial susceptibility in clinically relevant bacterial isolates plays an important role in the management of infectious diseases. The Tigecycline Evaluation and Surveillance Trial (TEST) is an ongoing worldwide surveillance programme monitoring the in vitro activity of tigecycline and a panel of representative comparator antibiotics. We report longitudinal susceptibility data on a large set of isolates (n=36,044) from clinically significant bacterial species collected in 25 microbiological laboratories from 2006 to 2014. Trends include a strong increase of carbapenem and levofloxacin resistance in

Indexed as

antimicrobial susceptibilityextended-spectrum beta-lactamaseGermanymethicillin-resistant Staphylococcus aureusmultidrug resistancetigecyclineTigecycline Evaluation and Surveillance Trial (TEST)vancomycin-resistant enterococci

Identifiers

PMID30671321
PMCPMC6301736

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.