Evidence map›Paper›PMID 30671228›Full record

ReviewCell regeneration (London, England)2018

Illumination of neural development by

Mingrui Xu, Jingjing Wang, Xize Guo, Tingting Li, Xia Kuang, Qing-Feng Wu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell regeneration (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mingrui XuInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Jingjing WangInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Xize GuoInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Tingting LiInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Xia KuangInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Qing-Feng WuInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single embryonic and adult neural stem cells (NSCs) are characterized by their self-renewal and differentiation potential. Lineage tracing via clonal analysis allows for specific labeling of a single NSC and tracking of its progeny throughout development. Over the past five decades, a plethora of clonal analysis methods have been developed in tandem with integration of chemical, genetic, imaging and sequencing techniques. Applications of these approaches have gained diverse insights into the heterogeneous behavior of NSCs, lineage relationships between cells, molecular regulation of fate specification and ontogeny of complex neural tissues. In this review, we summarize the history and methods of clonal analysis as well as highlight key findings revealed by single-cell lineage tracking of stem cells in developing and adult brains across different animal models.

Indexed as

In vivo clonal analysisLineage tracingNeural developmentNeural stem cellsNuclear brain structure

Identifiers

PMID30671228
PMCPMC6326247

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.