Evidence map›Paper›PMID 30671169›Full record

ArticleOxidative medicine and cellular longevity2018

Association of Impaired Reactive Aldehyde Metabolism with Delayed Graft Function in Human Kidney Transplantation.

Leonie G M Wijermars, Alexander F Schaapherder, Thomas George, Pritam Sinharoy, Eric R Gross

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Leonie G M WijermarsDepartment of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, Netherlands.
Alexander F SchaapherderDepartment of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, Netherlands.
Thomas GeorgeDepartment of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, 300 Pasteur Drive H3580, Stanford, 94305-5640 California, USA.
Pritam SinharoyDepartment of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, 300 Pasteur Drive H3580, Stanford, 94305-5640 California, USA.
Eric R GrossDepartment of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, 300 Pasteur Drive H3580, Stanford, 94305-5640 California, USA.ORCID 0000-0002-0589-6446
Stanford University · USLeiden University Medical Center · NL

Funding

Precision Targeting of Aldehyde Pathways for Patients Requiring AnesthesiaR35GM119522 · NIGMS · STANFORD UNIVERSITY · PI Eric Richard Gross · 2016 to 2026
$5.1M
NIGMS NIH HHS R35 GM119522
6 · The paper itself

Abstract

Delayed graft function is an early complication following kidney transplantation with an unclear molecular mechanism. Here we determined whether impaired reactive aldehyde metabolism is associated with delayed graft function. Human kidney biopsies from grafts with delayed graft function were compared with grafts that did not develop delayed graft function by Ingenuity gene pathway analysis. A second series of grafts with delayed graft function (

Indexed as

Gene Expression Regulation, DevelopmentalGraft SurvivalKidney TransplantationUp-RegulationAdultAldehyde DehydrogenaseAldehydesAldo-Keto ReductasesFemaleGlutathione TransferaseHumansKidneyMaleMiddle AgedAldehyde DehydrogenaseAldehydesAldo-Keto ReductasesGlutathione TransferaseGSTA1 protein, human

Identifiers

PMID30671169
PMCPMC6323462
OpenAlexW2906573705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.