Evidence map›Paper›PMID 30671119›Full record

ArticleLaboratory animal research2018

CRISPR/Cas9-mediated knockout of

Joo-Il Kim, Jin-Sung Park, Jina Kwak, Hyun-Jin Lim, Soo-Kyung Ryu, Euna Kwon, Kang-Min Han, Ki-Taek Nam, Han-Woong Lee, Byeong-Cheol Kang

Open access · diamondAbstract read
In one paragraph

Article in Laboratory animal research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Joo-Il KimGraduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jin-Sung ParkDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Jina KwakDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Hyun-Jin LimGraduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Korea.
Soo-Kyung RyuDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Euna KwonDepartment of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Kang-Min HanGraduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ki-Taek NamCollege of Medicine Severance Biomedical Science Institute, Yonsei University, Seoul, Korea.
Han-Woong LeeDepartment of Biochemistry, Yonsei University, Seoul, Korea.
Byeong-Cheol KangGraduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Korea.
Seoul National University Hospital · KRSeoul National University · KRNational University College · PRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD47 (integrin-associated protein), a multi-spanning transmembrane protein expressed in all cells including red blood cells (RBCs) and leukocytes, interacts with signal regulatory protein α (SIRPα) on macrophages and thereby inhibits phagocytosis of RBCs. Recently, we generated a novel C57BL/6J

Indexed as

CD47CRISPR/Cas9hemolytic anemiasplenomegaly

Identifiers

PMID30671119
PMCPMC6333621
OpenAlexW2910362647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.