Evidence map›Paper›PMID 30671114›Full record

ArticleLaboratory animal research2018

Generation of knockout mouse models of cyclin-dependent kinase inhibitors by engineered nuclease-mediated genome editing.

Bo Min Park, Jae-Il Roh, Jaehoon Lee, Han-Woong Lee

Open access · diamondAbstract read
In one paragraph

Article in Laboratory animal research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. BRAF inhibition increases TGFβ2 production and stimulates metastasis in mice with endogenous BRAFProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Effect of PIERCE1 on colorectal cancer.Experimental animals · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bo Min ParkDepartment of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.
Jae-Il RohDepartment of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.
Jaehoon LeeDepartment of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.
Han-Woong LeeDepartment of Biochemistry, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell cycle dysfunction can cause severe diseases, including neurodegenerative disease and cancer. Mutations in cyclin-dependent kinase inhibitors controlling the G1 phase of the cell cycle are prevalent in various cancers. Mice lacking the tumor suppressors

Indexed as

CRISPR/Cas9cyclin-dependent kinase inhibitorTALEN

Identifiers

PMID30671114
PMCPMC6333600
OpenAlexW2909317475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.