Evidence map›Paper›PMID 30671100›Full record

ReviewLaboratory animal research2018

Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes.

Hyeonhui Kim, Minki Kim, Sun-Kyoung Im, Sungsoon Fang

Abstract readReview
In one paragraph

Review in Laboratory animal research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 204 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Rewiring of NestinNeuroscience bulletin · 2026
    Article
  5. The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026
    Review
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144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyeonhui KimSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Minki KimSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Sun-Kyoung ImSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
Sungsoon FangSeverance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetically engineered mouse models are commonly preferred for studying the human disease due to genetic and pathophysiological similarities between mice and humans. In particular, Cre-

Indexed as

Cre-loxP systemCre portal sitestissue specific promoter

Identifiers

PMID30671100
PMCPMC6333611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.