ArticleHeredity2019
The genetic architecture of adaptation: convergence and pleiotropy in Heliconius wing pattern evolution.
Article in Heredity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- ERICA-trio: an outgroup-free deep learning method for topology inference and introgression detection.Briefings in bioinformatics · 2026Article
- Balanced polymorphism underlies long-standing adaptation for seasonal camouflage in the least weasel.Communications biology · 2026Article
- The Genomics of Convergent Adaptation to Intertidal Gravel Beaches in Mediterranean Clingfishes.Genome biology and evolution · 2026Article
- A model-free method for genealogical inference without phasing and its application for topology weighting.Genetics · 2026Article
- Evo-devo and the Biodiversity Crisis.Results and problems in cell differentiation · 2026Article
- Convergent evolution of noncoding elements associated with short tarsus length in birds.BMC biology · 2025Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Review
- Integrated miRNA and transcriptome profiling to explore the molecular determinism of convergent adaptation to corn in two lepidopteran pests of agriculture.BMC genomics · 2021Article
- Article
- Rampant Genome-Wide Admixture across the Heliconius Radiation.Genome biology and evolution · 2021Article
- Impact of male trait exaggeration on sex-biased gene expression and genome architecture in a water strider.BMC biology · 2021Article
- Growth genes are implicated in the evolutionary divergence of sympatric piscivorous and insectivorous rainbow trout (Oncorhynchus mykiss).BMC ecology and evolution · 2021Article
- The comparative genomic landscape of adaptive radiation in crater lake cichlid fishes.Molecular ecology · 2021Article
- The evolution and genetics of sexually dimorphic 'dual' mimicry in the butterflyProceedings. Biological sciences · 2021Article
- Deep Convergence, Shared Ancestry, and Evolutionary Novelty in the Genetic Architecture ofGenetics · 2020Article
- Many functionally connected loci foster adaptive diversification along a neotropical hybrid zone.Science advances · 2020Article
- Perfect mimicry betweenProceedings. Biological sciences · 2020Article
- Developmental constraints on fin diversity.Development, growth & differentiation · 2020Review
- Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation.PLoS biology · 2020Article
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Authors and funding
7 authors.
Funding
Abstract
Unravelling the genetic basis of adaptive traits is a major challenge in evolutionary biology. Doing so informs our understanding of evolution towards an adaptive optimum, the distribution of locus effect sizes, and the influence of genetic architecture on the evolvability of a trait. In the Müllerian co-mimics Heliconius melpomene and Heliconius erato some Mendelian loci affecting mimicry shifts are well known. However, several phenotypes in H. melpomene remain to be mapped, and the quantitative genetics of colour pattern variation has rarely been analysed. Here we use quantitative trait loci (QTL) analyses of crosses between H. melpomene races from Peru and Suriname to map, for the first time, the control of the broken band phenotype to WntA and identify a ~100 kb region controlling this variation. Additionally, we map variation in basal forewing red-orange pigmentation to a locus centred around the gene ventral veins lacking (vvl). The locus also appears to affect medial band shape variation as it was previously known to do in H. erato. This adds to the list of homologous regions controlling convergent phenotypes between these two species. Finally we show that Heliconius wing-patterning genes are strikingly pleiotropic among wing pattern traits. Our results demonstrate how genetic architecture can shape, aid and constrain adaptive evolution.
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