Evidence map›Paper›PMID 30670762›Full record

ArticleMucosal immunology2019

Two distinct colonic CD14

Laurence Chapuy, Marwa Bsat, Siranush Sarkizova, Manuel Rubio, Amélie Therrien, Evelyne Wassef, Mickael Bouin, Katarzina Orlicka, Audrey Weber, Nir Hacohen and 2 more

Erratum issuedOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Gut microbes · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Guselkumab binding to CD64Frontiers in immunology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Laurence ChapuyImmunoregulation Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, QC, Canada.
Marwa BsatImmunoregulation Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, QC, Canada.
Siranush SarkizovaDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Manuel RubioImmunoregulation Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, QC, Canada.
Amélie TherrienImmunoregulation Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, QC, Canada.
Evelyne WassefImmunoregulation Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, QC, Canada.
Mickael BouinCentre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal, Montréal, QC, Canada.
Katarzina OrlickaCentre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal, Montréal, QC, Canada.
Audrey WeberCentre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal, Montréal, QC, Canada.
Nir HacohenBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Alexandra-Chloé VillaniBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Marika SarfatiImmunoregulation Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Université de Montréal, Montréal, QC, Canada. m.sarfati@umontreal.ca.
Centre Hospitalier de l’Université de Montréal · CABroad Institute · USHarvard University · USMassachusetts General Hospital · US

Funding

Training Program in Bioinformatics and Integrative GenomicsT32HG002295 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Peter J Park · 2001 to 2026
$15.8M
Center for Cell CircuitsP50HG006193 · NHGRI · BROAD INSTITUTE, INC. · PI REGEV, AVIV · 2011 to 2015
$15.6M
Cancer Immunology Training GrantT32CA207021 · NCI · DANA-FARBER CANCER INST · PI WUCHERPFENNIG, KAI W · 2016 to 2020
$2.4M
CIHR MOP130533NCI NIH HHS T32 CA207021NHGRI NIH HHS P50 HG006193NHGRI NIH HHS T32 HG002295
6 · The paper itself

Abstract

Inflammatory bowel diseases are associated with dysregulated immune responses in the intestinal tissue. Four molecularly identified macrophage subsets control immune homeostasis in healthy gut. However, the specific roles and transcriptomic profiles of the phenotypically heterogeneous CD14

Indexed as

AdultCells, CulturedColonCrohn DiseaseCytokinesDisease ProgressionFemaleGene Expression ProfilingHumansImmunologic MemoryInflammation MediatorsLipopolysaccharide ReceptorsLymphocyte ActivationMacrophagesMaleSequence Analysis, RNACytokinesInflammation MediatorsLipopolysaccharide Receptors

Identifiers

PMID30670762
OpenAlexW2913950762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.