Evidence map›Paper›PMID 30670648›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy.

Yue Sun, Feng Ding, Zhixuan Zhou, Chonglu Li, Maoping Pu, Yuling Xu, Yibei Zhan, Xiaoju Lu, Haibing Li, Guangfu Yang and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Molecular fluorophores for in vivo bioimaging in the second near-infrared window.European journal of nuclear medicine and molecular imaging · 2022
    Pooled it
  2. Review
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  5. Review
  6. Review
  7. Design and synthesis of a small molecular NIR-II chemiluminescence probe for in vivoProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Metal-Coordinated Supramolecular Self-Assemblies for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  14. Anthracene-induced formation of highly twisted metallacycle and its crystal structure and tunable assembly behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Review
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yue SunKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China.
Feng DingKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China.
Zhixuan ZhouDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112.
Chonglu LiKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China.
Maoping PuInstitute of Organic Chemistry, Rheinisch-Westfälische Technische Hochschule Aachen University, 52074 Aachen, Germany.
Yuling XuKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China.
Yibei ZhanSchool of Chemistry and Chemical Engineering, Hubei Polytechnic University, Huangshi 435003, China.
Xiaoju LuSchool of Chemistry and Chemical Engineering, Hubei Polytechnic University, Huangshi 435003, China.
Haibing LiKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China; lhbing@mail.ccnu.edu.cn gfyang@mail.ccnu.edu.cn sunyaogbasp@mail.ccnu.edu.cn stang@chem.utah.edu.
Guangfu YangKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China; lhbing@mail.ccnu.edu.cn gfyang@mail.ccnu.edu.cn sunyaogbasp@mail.ccnu.edu.cn stang@chem.utah.edu.
Yao SunKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, China; lhbing@mail.ccnu.edu.cn gfyang@mail.ccnu.edu.cn sunyaogbasp@mail.ccnu.edu.cn stang@chem.utah.edu.
Peter J StangDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112; lhbing@mail.ccnu.edu.cn gfyang@mail.ccnu.edu.cn sunyaogbasp@mail.ccnu.edu.cn stang@chem.utah.edu.

Funding

Active Delivery of Platinum Nanoimmunoconjugates to Improve Breast Cancer TherapyR01CA215157 · NCI · PROTEOGENOMICS RESEARCH INSTIT/SYS/ MED · PI OLENYUK, BOGDAN, STANG, PETER J · 2017 to 2021
$2.3M
NCI NIH HHS R01 CA215157
6 · The paper itself

Abstract

Fluorescent theranostics probes at the second near-IR region (NIR-II; 1.0-1.7 µm) are in high demand for precise theranostics that minimize autofluorescence, reduce photon scattering, and improve the penetration depth. Herein, we designed and synthesized an NIR-II theranostic nanoprobe 1 that incorporates a Pt(II) metallacycle 2 and an organic molecular dye 3 into DSPE-mPEG5000 (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-

Indexed as

AnimalsMagnetic Resonance ImagingMiceMice, Inbred C57BLNeoplasmsNeoplasms, ExperimentalPhotonsSignal-To-Noise RatioTheranostic Nanomedicineimage-guided therapymetallacyclesecond near-infrared regionsupramolecular coordination complexestheranostic

Identifiers

PMID30670648
PMCPMC6369813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.