ArticleProceedings of the National Academy of Sciences of the United States of America2019
Dopamine modulates the reward experiences elicited by music.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05505019 (The Role of a Personalized Music Intervention Towards Alleviating Apathy in Parkinson's Disease), which is not on this map. Cited by 153 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of a Personalized Music Intervention Towards Alleviating Apathy in Parkinson's Disease
Who cites it
153 citing papers in PubMed, 8 syntheses or guidelines pooled it, 418 citations in OpenAlex.
- Music and trust formation: a scoping review of neurobiological convergence and research priorities.Frontiers in psychology · 2026Pooled it
- Cognitive enhancement through music therapy: meta-analytic evidence across clinical population.Frontiers in public health · 2025Pooled it
- Music in the loop: a systematic review of current neurofeedback methodologies using music.Frontiers in neuroscience · 2025Pooled it
- Does music counteract mental fatigue? A systematic review.PloS one · 2025Pooled it
- Effect of music therapy on anxiety and depression in breast cancer patients: systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Musicotherapy mobile applications: what level of evidence and potential role in psychiatric care? A systematic review.Frontiers in psychiatry · 2024Pooled it
- Effects of Music on Attention-Deficit/Hyperactivity Disorder (ADHD) and Potential Application in Serious Video Games: Systematic Review.Journal of medical Internet research · 2023Pooled it
- How to Tackle Mental Fatigue: A Systematic Review of Potential Countermeasures and Their Underlying Mechanisms.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Acquisition of musical skills and abilities in older adults-results of 12 months of music training.BMC geriatrics · 2024Trial
- Cognitive enrichment through art: a randomized controlled trial on the effect of music or visual arts group practice on cognitive and brain development of young children.BMC complementary medicine and therapies · 2024Trial
- Vocal music enhances memory and language recovery after stroke: pooled results from two RCTs.Annals of clinical and translational neurology · 2020Trial
- Musical Episodic Modulation of Human Functioning: Anticipation Mechanisms, Personal Sense, and Emotional Recall.Integrative psychological & behavioral science · 2026Article
- Music Enjoyment in Hearing Loss: Beyond Auditory Perception.Brain sciences · 2026Review
- Music and Exercise in Concert: Uncovering Synergistic Mechanisms for Enhancing Brain Health and Cognitive Resilience-A Narrative Review.Brain and behavior · 2026Review
- Successful reinforcement history suppresses explicit and implicit error corrections.PLoS computational biology · 2026Article
- Toward precision music medicine in oncology care: reproducible, scalable and biomarker-driven interventions.EClinicalMedicine · 2026Review
- Music engages the phasic dopaminergic D1-receptor system in humans: a PET-fMRI study using [European journal of nuclear medicine and molecular imaging · 2026Article
- Music Listening in Medicine and Healthcare: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Listening to a Consonant Chord Progression during Live Face-to-Face Gaze Enhances Neural Activity in Social Systems.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Single-session music therapy reduces anxiety and depression among hospitalized adults in an endocrinology ward.Clinics (Sao Paulo, Brazil) · 2026Article
93 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding how the brain translates a structured sequence of sounds, such as music, into a pleasant and rewarding experience is a fascinating question which may be crucial to better understand the processing of abstract rewards in humans. Previous neuroimaging findings point to a challenging role of the dopaminergic system in music-evoked pleasure. However, there is a lack of direct evidence showing that dopamine function is causally related to the pleasure we experience from music. We addressed this problem through a double blind within-subject pharmacological design in which we directly manipulated dopaminergic synaptic availability while healthy participants (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.