Evidence map›Paper›PMID 30670547›Full record

ArticleJournal of bacteriology2019

PmrC (EptA) and CptA Negatively Affect Outer Membrane Vesicle Production in Citrobacter rodentium.

Anshul Sinha, Sammy Nyongesa, Charles Viau, Samantha Gruenheid, Frédéric J Veyrier, Hervé Le Moual

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  7. Article
  8. Article
  9. Outer Membrane Vesicles: Biogenesis, Functions, and Issues.Microbiology and molecular biology reviews : MMBR · 2022
    Review
  10. Remodeling of Lipid A inInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anshul SinhaDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Sammy NyongesaINRS-Institut Armand-Frappier, Bacterial Symbionts Evolution, Laval, Quebec, Canada.
Charles ViauDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
Samantha GruenheidDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada samantha.gruenheid@mcgill.ca frederic.veyrier@iaf.inrs.ca.
Frédéric J VeyrierINRS-Institut Armand-Frappier, Bacterial Symbionts Evolution, Laval, Quebec, Canada samantha.gruenheid@mcgill.ca frederic.veyrier@iaf.inrs.ca.
Hervé Le MoualDepartment of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
McGill University · CAInstitut National de la Recherche Scientifique · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outer membrane vesicles (OMVs) are naturally produced by Gram-negative bacteria by a bulging of the outer membrane (OM) and subsequent release into the environment. By serving as vehicles for various cargos, including proteins, nucleic acids and small metabolites, OMVs are central to interbacterial interactions and both symbiotic and pathogenic host bacterial interactions. However, despite their importance, the mechanism of OMV formation remains unclear. Recent evidence indicates that covalent modifications of lipopolysaccharides (LPS) influence OMV biogenesis. Several enteric bacteria modify LPS with phosphoethanolamine (pEtN) using the iron-regulated PmrC (EptA) and CptA pEtN transferases. In wild-type

Indexed as

Bacterial ProteinsCitrobacter rodentiumEndopeptidasesEthanolaminephosphotransferaseExtracellular VesiclesGene DeletionGenetic Complementation TestIronBacterial ProteinsCptA protein, bacteriaEndopeptidasesEthanolaminephosphotransferaseIronCitrobacter rodentiumenvelope stress responseLPS modificationsouter membrane vesiclesoxidative stresstwo-component regulatory systems

Identifiers

PMID30670547
PMCPMC6416907
OpenAlexW2914627183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.